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Showing 1 to 20 of 91 for “"Settore MED/04 - Patologia Generale"”.

  1. CHARACTERIZATION OF GENETIC AND EPIGENETIC MODIFICATIONS IN A MODEL OF INFLAMMATION-DRIVEN CANCER

    Chronic inflammation is causally associated to many types of tumor, and has been recently acknowledged as a cancer hallmark. Nevertheless, whether inflammation has an intrinsic mutagenic potential is still not directly proven or understood from a mechanistic point of view. Furthermore, it is as yet …

    milano Repository record for CHARACTERIZATION OF GENETIC AND EPIGENETIC MODIFICATIONS IN A MODEL OF INFLAMMATION-DRIVEN CANCER (opens in a new tab)

  2. NOVEL APPROACHES IN GENETIC VARIANT DISCOVERY AND CLASSIFICATION TACKLING UNSOLVED PROBLEMS IN CANCER CLINICAL GENOMICS

    … diagnosis and targeted therapy in personalized medicine. However, variant classification is a complex process that requires the integration of multiple, often incomplete sources of information, prompting the development of bioinformatic tools that enable clinicians to prioritize mutations for …

    milano Repository record for NOVEL APPROACHES IN GENETIC VARIANT DISCOVERY AND CLASSIFICATION TACKLING UNSOLVED PROBLEMS IN CANCER CLINICAL GENOMICS (opens in a new tab)

  3. REDEFINING PROMOTER DNA METHYLATION CHANGE IN CANCER

    Promoter DNA methylation has been recognized for decades as one of the major mechanisms of epigenetic gene regulation and has consistently been found to be perturbed during cancer development. However, among the many genomic regions that have been found to display altered methylation in different …

    milano Repository record for REDEFINING PROMOTER DNA METHYLATION CHANGE IN CANCER (opens in a new tab)

  4. Mechanisms of chemoresistance in distinct cancer cell lines

    unito Repository record for Mechanisms of chemoresistance in distinct cancer cell lines (opens in a new tab)

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