Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"Settore BIO/16 - Anatomia Umana"”.
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IMPAIRMENT OF TOLL-LIKE RECEPTOR 9 AGONIST ANTI-TUMOR ACTIVITY BY ANTI-PD-1 ANTIBODY: ROLE OF MACROPHAGES
… profilo di espressione genica seguite da analisi bioinformatiche, Real-time PCR, multiplex ELISA e saggi di rilascio del 51Cr. Per investigare il ruolo specifico del sito di legame con l’antigene e del dominio del frammento cristallizzabile (Fc) dell’anticorpo anti-PD-1, sono stati utilizzati …
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Finding the missing connection: diffusion-based tractography reconstruction of the acoustic radiation and other applications
… of tracking methods, with applications in neurobiological and clinical research. In particular, the main work focuses on a white matter bundle that represents a notable omission in tractography studies: the acoustic radiation (AR), a major projection sensory pathway conveying auditory …
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VGF: a novel and predictive biomarker of Parkinson’s disease
… motor impairments. Identifying reliable biomarkers capable of detecting PD during these early stages remains a major clinical challenge. VGF is a neurosecretory precursor protein that undergoes extensive processing to generate multiple neuronal products (peptides/proteins) with …
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Gene inducibile VGF e surrene. Prodotti derivati da proVGF, distribuzione differenziale, possibile modulazione
Il gene “VGF” fu scoperto perché è uno dei prodotti più potentemente indotti da NGF (NERVE GROWTH FACTOR) in cellule di feocromocitoma di ratto, in coincidenza con il loro passaggio ad un fenotipo neuronale indotto dal NGF stesso. Un primo trascritto è tradotto nel precursore proVGF, che è …
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Fattori prognostici nel melanoma cutaneo e nel tumore mammario associati a caratteristiche molecolari simil-staminali
… laser scanning microscopy were performed on biopsy specimens of cutaneous melanoma from 81 patients and in breast carcinomas from 53 patients. In melanoma, Fisher’s and Pearson’s tests showed a correlation between nestin, vimentin and subcellular GR location (P = 0.008). Their concomitant …
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Il Δ9-THC, componente principale della cannabis sativa, attenua la neurotossicità indotta dalla meth
… with the CB1 rceptor antagonist SR141716A (SR). SR partially blocked METH-induced nNOS-overexpression but failed to revert the decreasing effect of Δ9-THC on METH-induced GFAP-immunostaining. These results indicate that Δ9-THC reduces METH-induced brain damage by CB1-dependent and …
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THREE-DIMENSIONAL FACIAL ANTHROPOMETRY
The use of 3D surface technology is progressively increasing in health clinics and research centers. Methods of capturing 3D facial surface may obtain more imaging information providing a reliable and fast analysis. Stereophotogrammetry is a promising method of soft-tissue evaluation that allows …
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VIRTUAL ANTHROPOLOGY AND COMMINGLED SKELETAL REMAINS. RESOURCES AND POTENTIAL FOR PERSONAL IDENTIFICATION IN HUMANITARIAN FORENSIC CONTEXTS
Commingled skeletal remains represent a compelling topic in forensic anthropology, especially in view of the recent mass disasters in the Mediterranean Sea related to the migration crisis. With over 1,000 alleged victims, and thousands of commingled skeletal remains, the shipwreck of April, 8th, …
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Caratterizzazione dimensionale e morfologica di nanoparticelle lipidiche contenenti molecole farmacologicamente attive
With the advent of nanotechnology, great interest is being dedicated to the interactions of nanomaterials/nanoparticles with human beings. All the interactions occurring due to an intentional exposure are investigated by a new research field named Nanomedicine. As this name may suggest, the use of …
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Lesioni degenerative e meccanismi di riparo della superficie oculare: lo pterigio e le deficienze delle cellule staminali del limbo (LSCD). Studio immunoistochimico e tecniche di coltura cellulare
Pterygium is a surface ocular lesion that is associated with chronic UV exposure, characterized by proliferation, inflammatory infiltrates, fibrosis, angiogenesis and extracellular matrix remodeling. The Angiotensin converting enzyme (ACE or ACE I) is the major component of the Renin-angiotensin …
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IMMUNOMODULATION AND INTESTINAL BARRIER PROTECTION ACTIVITIES OF A NOVEL SYNTHETIC GLUCOSE ANALOGUE IN INFLAMMATORY ANIMAL MODEL OF COLITIS AND ASTHMA.
The mucosal surfaces of the gastrointestinal and respiratory tracts are the main interfaces between the environment and the host. All two are protected by continuous epithelia that prevents the entry of microbes and integrity loss of these epithelia commonly predispose to infection. On the other …
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VGF e stress ossidativo: alterazioni cellulari e modulazione nella Sclerosi Laterale Amiotrofica
… vivo to various low MW peptides with different biologic activities. These include attenuation of excytotoxic injury on spinal motor neurons from G93A-SOD-1 mice, upon overexpression of the VGF precursor, or an anti-apoptotic action of the VGF peptide TLQP-21 on cerebellar granules. Recently, the …
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