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Showing 1 to 20 of 65 for “"Settore BIO/13 - Biologia Applicata"”.

  1. ALTERAZIONI MICROSCOPICHE DELLA DECOMPOSIZIONE:IMPLICAZIONI PER LA MEDICINA LEGALE

    … histological, histochemical, ultrastructural and biochemical analyses have been proposed. The differential diagnosis between vital and post-mortem bone injuries may be more difficult both during macroscopic and microscopic examination: also in these cases histological, histochemical, biochemical …

    milano Repository record for ALTERAZIONI MICROSCOPICHE DELLA DECOMPOSIZIONE:IMPLICAZIONI PER LA MEDICINA LEGALE (opens in a new tab)

  2. DISSECTING THE MOLECULAR MECHANISMS RELATED TO THE ONSET OF NEUROLOGICAL COMPLICATIONS IN THREE CELLULAR MODELS OF SARS-COV 2 INFECTION: IPSC-DERIVED MOTO R NEURONS, IPSC-DERIVED DOPAMINERGIC NEURONS, IPSC DERIVED-HUMAN CORTICAL ORGANOIDS.

    … Such information will be important to unveil the biological bases of neuromuscular disorders characterizing SARS-CoV-2 infection and the so called long-COVID symptoms. At the same time, we observed that iPSC-Human Cortical Organoids (HCO) were productively infected by SARS-CoV-2, probably by …

    milano Repository record for DISSECTING THE MOLECULAR MECHANISMS RELATED TO THE ONSET OF NEUROLOGICAL COMPLICATIONS IN THREE CELLULAR MODELS OF SARS-COV 2 INFECTION: IPSC-DERIVED MOTO R NEURONS, IPSC-DERIVED DOPAMINERGIC NEURONS, IPSC DERIVED-HUMAN CORTICAL ORGANOIDS. (opens in a new tab)

  3. ZEBRAFISH (DANIO RERIO) AS A MODEL SYSTEM FOR THE FUNCTIONALVALIDATION OF CANDIDATE GENES FOR HUMAN DISEASES

    In recent years, zebrafish (Danio rerio) has become increasingly utilized as a model for studying human gene functions and associated diseases. This has been possible due to the very high conservation of genes and of organs and systems which are fully functional within the very first days of …

    milano Repository record for ZEBRAFISH (DANIO RERIO) AS A MODEL SYSTEM FOR THE FUNCTIONALVALIDATION OF CANDIDATE GENES FOR HUMAN DISEASES (opens in a new tab)

  4. NEURAL PRECURSOR/STEM CELL-BASED THERAPY: A NOVEL THERAPEUTIC APPROACH FOR THE TREATMENT OF RETT SYNDROME

    … on brain of the same transplanted animals. Bioinformatics analyses revealed several deregulated pathways, mostly upregulated and associated with the immune system, in Mecp2 KO mice treated with NPCs compared to the control group. Among these pathways emerged the upregulation of that one …

    milano Repository record for NEURAL PRECURSOR/STEM CELL-BASED THERAPY: A NOVEL THERAPEUTIC APPROACH FOR THE TREATMENT OF RETT SYNDROME (opens in a new tab)

  5. VOLTAGE GATED SODIUM CHANNEL AND NEURONAL DIFFERENTIATION. IMPLICATIONS IN AMYOTROPHIC LATERAL SCLEROSIS PATHOGENESIS

    Voltage gated sodium channels (VGSCs) are multimeric protein complexes formed by one alpha subunit, responsible of pore formation and of the regulation of the state of the channel, and by one or two accessory beta subunits that have an important role in the regulation of alpha subunit localization …

    milano Repository record for VOLTAGE GATED SODIUM CHANNEL AND NEURONAL DIFFERENTIATION. IMPLICATIONS IN AMYOTROPHIC LATERAL SCLEROSIS PATHOGENESIS (opens in a new tab)

  6. CROSS-DISEASE ANALYSIS OF MOLECULAR AND CELLULAR MECHANISMS IN KIF5A-ASSOCIATED NEURODEGENERATIVE DISORDERS

    … substrates. Interestingly, the aberrant biochemical behaviour of the ALS mutant N999Vfs*40 KIF5A was more severely recapitulated by the NEIMY mutant C975Vfs*73 KIF5A, which shares the last portion of its abnormal C-terminal tail yet causes a neurodevelopmental disorder, on the opposite …

    milano Repository record for CROSS-DISEASE ANALYSIS OF MOLECULAR AND CELLULAR MECHANISMS IN KIF5A-ASSOCIATED NEURODEGENERATIVE DISORDERS (opens in a new tab)

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