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Showing 1 to 12 of 12 for “"Settore BIO/12 - Biochimica Clinica e Biologia Molecolare Clinica"”.

  1. PRECLINICAL PET IMAGING FOR TUMOUR CHARACTERIZATION: FOCUS ON HYPOXIA AND INFLAMMATION

    S. ValtortaUniversità degli Studi di Milano2010

    … has allowed the use of these methods in preclinical research with the possibility to transfer directly the obtained results in clinic. In this thesis’s work we characterized two preclinical oncology models through the use of an animal PET instrument focusing on two processes correlated to …

    milano Repository record

  2. Decoding endothelial cell polarity: how PPFIA1 coordinates Golgi secretion and adhesion site turnover

    Serini, Guido, Clapero, FabianaUniversità degli Studi di Torino2019

    unito Repository record

  3. Acquired resistance to targeted therapies in BRAF mutant colorectal cancer

    Di Nicolantonio, Federica, Oddo, DanieleUniversità degli Studi di Torino2018

    unito Repository record

  4. NUTRITIONAL STATUS OF SCHOOLING CHILDREN IN TANZANIA AND UGANDA: RESEARCH AND ACTION

    COMANDINI, ORNELLAUniversità degli Studi di Cagliari2017

    … We have assessed the nutritional status of 1254 children, 423 in Tanzania and 831 in Uganda, in five schools with different social, cultural and environmental characteristics. Bumbire island (Tanzania) children show high levels of undernutrition (stunting = 31%; underweight = 13%), which …

    cagliari Repository record

  5. Caratteristiche morfometriche della popolazione sarda dal Neolitico al XIX secolo: craniometria e statura

    MARTELLA, PATRIZIAUniversità degli Studi di Cagliari2017

    … in order to improve the knowledge of history and biological characteristic of the Sardinians. The study of skeletal material has allowed to evaluate morphological changes in time and space, to determinate the variability within population and, when possible, to make comparisons with other past and …

    cagliari Repository record

  6. Definizione e applicazione di metodologie per la valutazione della composizione corporea e del volume dell’arto superiore

    MEREU, ELENAUniversità degli Studi di Cagliari2017

    Background: Specific Bioelectrical Impedance Vector Analysis (BIVAsp) is an easy to use, inexpensive, non invasive, and accurate technique for the assessment of body composition (Buffa et al., 2013; Marini et al., 2013), which is promising for applications in many biomedical fields. Objective: This …

    cagliari Repository record

  7. Characterization of Ebola virus VP35-dsRNA binding for drug development against Ebola virus disease.

    DAINO, GIANLUCAUniversità degli Studi di Cagliari2017

    … in prokaryotic system and used to validate a biochemical pull-down assay for the screening of small molecules targeted to the VP35-double strand (ds)-RNA interactions. However, low rVP35 amount of purified protein and the use of radioactive substrate for binding evaluation, strongly limited …

    cagliari Repository record

  8. Exploring metabolomics through NMR: from early life to aging

    CANNAS, FEDERICOUniversità degli Studi di Cagliari2026

    … proximity to phenotype and its sensitivity to clinical and environmental perturbations make it a powerful tool for understanding biological processes in real-world settings. At the same time, this very sensitivity increases its vulnerability to confounding, analytical variability, and …

    cagliari Repository record

  9. MOLECULAR PATHWAYS ANALYSIS THROUGH MULTI-OMICS APPROACHES TO STUDY THE BIOLOGICAL BASIS OF ANOREXIA NERVOSA

    DONATO, KEVINUniversità degli Studi di Milano2025

    … tools for understanding the genetic and biochemical pathways involved in AN. This study aimed to investigate the genetic and metabolomic basis of AN using next-generation sequencing, polygenic risk scoring, and hair metabolomic profiling, with the ultimate goal of improving diagnosis and …

    milano Repository record

  10. CHARACTERIZATION OF PLACENTAL AUTOPHAGY AND BIOENERGETICS, AND MATERNAL MICRORNAS PROFILING IN OBESE PREGNANCIES AND GESTATIONAL DIABETES MELLITUS

    SERATI, ANAISUniversità degli Studi di Milano2023

    … placental autophagy and mitochondrial bioenergetics, and maternal plasmatic microRNAs profile in the context of MO and GDM. METHODS 60 women with spontaneous singleton pregnancies delivering by elective Caesarean section were enrolled: 25 normal-weight (NW), 22 obese without …

    milano Repository record

  11. INTEGRATION OF NUTRITIONAL SUPPORT IN ORTHOPEDICS: DIETARY AND NUTRITIONAL ASPECTS OF SURGICAL PATIENTS

    BRIGUGLIO, MATTEOUniversità degli Studi di Milano2022

    … The predictive potential of hemoglobin on the clinical outcome in spine surgery has been investigated through retrospective analysis of existing data, suggesting the need to refine decision-making algorithms that identify the patients to be treated, underlining the importance of having high …

    milano Repository record

  12. PERSPECTIVES ON THE CLINICAL APPLICATION OF LEWIS ANTIGENS IN PANCREATIC CANCER: TOWARDS A PERSONALIZED TUMOR MARKER STRATEGY

    INDELLICATO, ROSSELLAUniversità degli Studi di Milano2023

    … antibodies. Results. In 14 out of 118 patients (12%), ELISA on sera showed an increase in CA19.9 and/or Lea with respect to healthy controls. In all the patients, no significant statistical difference in glycosyltransferases expression was assessed by qPCR between normal and cancer tissue. 11 out …

    milano Repository record