Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"Sertraline"”.
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Occupations as an Outcome Measure in a Clinical Trial: Fragile X Syndrome and Sertraline
… of a randomized controlled medication trial of sertraline (Zoloft) on children two to six years old diagnosed with FXS. The constant comparison method was used to analyze differences in family expressions of their child’s improvements over the course of the 6-month clinical trial. Twelve …
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Effects of Sertraline Treatment for Young Children with Fragile X Syndrome: Family Perspectives via Case Studies
… examining four male participants who were given sertraline in an in-depth case study analysis. Caregivers were interviewed using a semi-structured interview protocol at baseline and at six months post-treatment to discuss their child, occupations, and any potential impacts of sertraline. Baseline …
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Analysis of the behavioural effects of barley and sertraline in two in-vivo models of stress.Anti-depressant and anti-nociceptive effects of barley in mice and sertraline effects on anxiety in the offspring of prenatally-stressed rats
… post-natal depression model, the antidepressant sertraline, was assessed in rat mothers (n=14) divided into Prenatally Stressed (PS) and Non-Stressed (NS) groups. The data failed to support the hypothesis that ‘the progeny of 10mg of sertraline-treated PS mothers displayed less anxiety than the …
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Analysis of the behavioural effects of barley and sertraline in two in-vivo models of stress.Anti-depressant and anti-nociceptive effects of barley in mice and sertraline effects on anxiety in the offspring of prenatally-stressed rats
… post-natal depression model, the antidepressant sertraline, was assessed in rat mothers (n=14) divided into Prenatally Stressed (PS) and Non-Stressed (NS) groups. The data failed to support the hypothesis that ‘the progeny of 10mg of sertraline-treated PS mothers displayed less anxiety than the …
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Living with Fragile X Syndrome: Occupations as an Outcome Measure in a Clinical Trial
… trial. Each participant received either sertraline or a placebo. The aim of this research was to assess differences in occupational functioning in the sertraline group and placebo group, that may not have been detected with the use quantitative outcome measures alone. Results showed …
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Unravelling Variability in Antidepressant Outcomes using Pharmacogenetic and Pharmacokinetic Strategies
… with psychotic depression were treated with sertraline and olanzapine for up to 20 weeks, followed by a randomized phase of 36 weeks when participants received sertraline and olanzapine or sertraline and placebo. Using genome-wide association studies (GWAS), we identified suggestive genomic …
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Life Cycle Assessment in Pharmaceutical Applications.
… at various stages of the development process for Sertraline Hydrochloride, an effective chiral antidepressant, was conducted. This evaluation included the Life Cycle Inventory (LCI) and further Life Cycle Assessment (LCA) to compare several synthetic routes and production processes of this …
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PARENTAL RESISTANCE IN COGNITIVE BHAVIORAL THERAPY FOR ANXIOUS YOUTH
… levels for participants in the CBT plus sertraline condition. Results: Analyses demonstrated that there was no significant difference in mean resistance scores between the CBT-only group and the CBT plus sertraline group. None of the 12 mediation tests found statistically significant …
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Innovative analytical methods for Central Nervous System Drug analysis in biological fluids
… in biological fluids, including antidepressants (sertraline and duloxetine), antipsychotics (aripiprazole), antiepileptics (vigabatrin and topiramate) and antiparkinsons (pramipexole). Innovative methods based on liquid chromatography or capillary electrophoresis coupled to diode-array or …
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Spatial and temporal analysis of pharmaceutical concentrations and chitobiase activity in the Upper Tennessee River
… ranitidine, ciprofloxacin, levofloxacin, sertraline, fluoxetine, norfluoxetine, diltiazem, lovastatin, and atorvastatin). The simultaneous method pre-concentrated analytes by a factor of 1000 with percent recoveries ranging from 44% to 104% and RSDs below 16%. Percent recoveries were …
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The elderly, arginine vasopressin & selective serotonin reuptake inhibitors
… found to be normal in six elderly patients using sertraline. In the elderly there are physiological changes, a high prevalence of medical illnesses and concomitant drug use which may precipitate hyponatraemia. Together with a risk of altered water regulation in psychiatric illness this may account …
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The Roles of Inflammation, Oxidative Stress, and Neurotransmitters in an Animal Model of Post-Traumatic Stress Disorder
… selective-serotonin reuptake inhibitor (SSRI) sertraline to ascertain why SSRIs have historically been ineffective in treating PTSD. Taken together, our findings indicate inflammation, oxidative stress, and aberrant neurotransmitter profiles may play a significant role in PTSD development and …
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Towards less hazardous chemicals : identifying chemical bioactivity through fish behavioral profiles.
… prescribed psychiatric medications, oxazepam and sertraline, on perch collected from natural waters. Results from this study identified time related effects on fish boldness and neuroactive pharmaceutical related effects on fish activity levels.
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Dearomative functionalization of simple arenes: Reduction and palladium-catalyzed syn-1,4-aminofunctionalizations
… This is highlighted by the facile synthesis of Sertraline, one of the best-selling antidepressant.
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Early environments and neurobehavioural programming: Therapeutic actions of antidepressants. Neurobehavioural programming during development.
… or an antidepressant (imipramine 15mg/kg; or sertraline 10mg/kg) once daily until postnatal day 10. We assessed maternal Porsolt activity, nurturance (ABN, L/G, nest building) and anxiety-like behaviour in the elevated plus maze (EPM). Representative offspring of each Dam¿s treatment …