Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Sequence polymorphism"”.
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Natural Selection on S-Linked Genes in Turnera (Passifloracease)
… in Turnera, average nucleotide diversity and sequence polymorphism measures were found to be elevated in two S-linked genes (AP2D and RNABP), suggesting the possible occurrence of balancing selection at these or closely-linked loci. Limited trans-species polymorphisms were identified in …
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Molecular Evolution of Viruses
… across the globe. Analysis of nucleotide sequence polymorphism in the genomic segments encoding the two most immunologically important proteins of influenza A, neuraminidase (NA) and hemagglutinin (HA), showed that the H1N1 (2009) has resulted from the spread of an HA segment of recent …
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Evolutionary, structural and functional features of cellular signalling networks
… amino acids in human proteins. By analysing sequence, polymorphism and mutation data at the species, population and individual levels, we observed significant evolutionary constraints on all PTM types for which extensive data was available, as well as overrepresentation of amino acids which …
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A genomic analysis using RNA-Seq to investigate the adaptation of the psychrophilic diatom Fragilariopsis cylindrus to the polar environment
… were applied. Comparative genomics with the sequenced mesophilic diatoms Phaeodactylum tricornutum and Thalassiosira pseudonana was combined with genome-wide RNA-Seq transcriptome analysis, leading to the discovery a new bacteria-like rhodopsin not present in other sequenced diatoms. The …
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Genetic studies of candidate genes in the glycoalkaloid biosynthetic pathway of potato
… candidate genes were amplified, cloned and sequenced [3-hydroxy-3-methylglutaryl coenzyme A reductase 1 and 2 (HMG1, HMG2); 2,3-squalene epoxidase (SQE); solanidine galactosyltransferase (SGT1); and solanidine glucosyltransferase (SGT2)]. A germplasm panel of six wild potato species [Solanum …
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Dual parametric sensors for highly sensitive nucleic acid detection
… reaction were measured using 10- mer nucleotide sequences. A 30-40% change in relative permittivity (capacitance) was observed due to DNA hybridization at 10Hz, which is much more sensitive than the previously reposted detection measurements (2-8% signal change). In parallel to the above work, a …
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Evolution of major histocompatibility complex genes in New World bats and their functional importance in parasite resistance and life-history decisions in the lesser bulldog bat (Noctilio albiventris)
… drivers of the typically-observed high levels of polymorphism in functionally important parts of the MHC. The recognition of the individual MHC constitution is presumed to be mediated through olfactory cues. Indeed, MHC genes are in physical linkage with olfactory receptor genes and alter the …
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Patterns of Selection In Hepatitis C and Hiv
… <p>Analysis of complete polyprotein-encoding sequences of the two most prevalent genotypes of Hepatitis C (HCV-1a and HCV-1b) showed evidence, not only of past purifying selection, but also of abundant slightly deleterious nonsynonymous variants subject to ongoing purifying selection. In the …