Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Senescence-like phenotype"”.
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The role of extracellular matrix remodelling in brown adipose tissue functions: New candidates
… upon activation conditions, while it induces a senescence-like phenotype in preadipocytes differentiated in vitro. In Chapter 6 and 7, we demonstrated that Cyr61 and Aplp2 play a significant role in ECM-mitochondrial crosstalk by different mechanisms, as the knock-down of either of them induces …
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Role of Bcl-xL in Doxorubicin-Induced Cell Death: Apoptosis and Mitotic Cell Death
… whether Bcl-xL overexpression affected senescence and/or mitotic cell death induced by LD of doxorubicin. Bcl-xL overexpression effectively blocked apoptosis induced by high dose HD of doxorubicin, blocking the loss of mitochondrial membrane potential and activation of caspases in Huh-7 …
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Regulatory Mechanisms of Mitotic Catastrophe Induced by Doxorubicin
… damage to cell membranes and induce apoptosis, senescence or mitotic catastrophe. Because low dose of doxorubicin induce senescence or mitotic cell death, we attempted to investigate the possible link between the drug-induced senescence and mitotic cell death as comparing with apoptotic cell …