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Showing 1 to 12 of 12 for “"Semliki forest virus"”.
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The Structure and Replication of Semliki Forest Virus, A Mosquito-Borne Animal Virus
<p>Semliki Forest virus is a group A arthropod-borne virus which contains RNA and possesses a lipoprotein envelope. It can be transmitted among animals by mosquitoes in which it multiplies, but its natural host is not known. The virus grows to high titer in a number of types of vertebrate cells in …
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HIV-1-derived lentiviral vectors pseudotyped with envelope glycoproteins derived from Ross River virus and SemlikI Forest virus
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Use of an Atg16l1 mouse model to study the role played by autophagy in neuroprotection
… To investigate autophagy in the context of virus‐host interaction, Semliki Forest Virus infection was tested in Atg16l1 KO tissues. Atg16l1 KO had no effect on virus proliferation in organotypic brain slice cultures while viral nsP1 and capsid expression was reduced in Atg16l1 KO embryonic …
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Produktion von monoklonalen Antikörpern und Phagenantikörpern gegen das Rinder-Prionprotein durch SFV Partikel-vermittelte Immunisierung von PrP0/0-Mäusen
… Teil der Arbeit wurden Mäuse mit rekombinanten Semliki-Forest-Virus (rSFV) Partikeln immunisiert und die mAks hergestellt. Anschließend wurden die Epitope dieser mAks charakterisiert. Im zweiten Teil der Arbeit wurden dann aus einigen Hybridklonen mittels eines rekombinanten …
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Characterization of the entry mechanisms utilized by the alphavirus venezuelan equine encephalitis virus to infect mosquito cells
… encephalitis eirus (VEEV) is a New World alphavirus that can cause fatal encephalitis in humans. VEEV is an enveloped, positive-strand RNA virus that is transmitted by a mosquito vector. Most research on alphavirus entry was done with the Old World alphavirus Semliki Forest virus (SFV) in …
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Investigating the effects of pH on alphaviral E3-E2 glycoprotein association, organization, and cellular tropism
<p>In alphaviruses the role of E3 is required in protecting the fusion peptide region of E1 during intracellular transport. Throughout viral processing, the association of E2 and E3 is required for the successful trafficking and incorporation of E1 into the mature virion. This E3-E2 association has …
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Effective Strategies for Preventing and Mitigating Emerging Viruses
… of pandemic proportion, with zoonotic RNA viruses such as chikungunya virus (CHIKV) and SARS-CoV-2 posing significant threats to global health. Several environmental and evolutionary factors have fueled the emergence and spread of infection, creating a constant arms race against emerging …
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Characterization of the 37-kDa/67-kDa laminin receptor as the cell surface receptor for the cellular prion protein
… (BHK) cells transfected with recombinant Semlik-Forest virus RNAs overexpressed human PrP and human LRP at their cell surface, the latter one orientated as a type II transmembrane protein with its C-terminus outside and its N-terminus inside the cell. Co-localization of both proteins was observed …