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Showing 1 to 11 of 11 for “"Selenium compounds"”.
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Molecular mechanisms mediating the induction of apoptosis by chemopreventive selenium compounds
… cell line, HeLa, molecular mediators of selenium-induced apoptosis were investigated. These studies were later extended to biopsies of normal human oral mucosa cells (NOMCs) and human oral carcinoma cells (SCCs), using a primary culture system. Two selenium compounds were tested: …
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Comparative safety, pharmacokinetic and pharmacodynamic evaluation of three oral selenium compounds in cancer patients
Selenium (Se) is an essential trace element involved in many biological processes in humans. Se compounds have demonstrated growth inhibition of malignant cells and tumours in many experimental models. Furthermore, combining Se with cancer therapies has yielded promising results in both preclinical …
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The mechanism of action of the anticancer effects of selenomethionine on colon cancer
Selenomethionine, an organic derivative of selenium, has been found to be the predominate selenium component of the dietary cancer chemopreventive agent selenized yeast that has been shown to decrease the incidence and mortality rate of lung, colon, and prostate cancers. Another organic selenium …
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Effects of sulfur complexation on intestinal transport and toxicity of metalloids in cell cultures
… poison and is classified as human carcinogen. Selenium is an essential nutrient, but is highly toxic when applied in high concentrations. The cytotoxic potential of both metalloids is modified when they form sulfur-containing complexes. For arsenic compounds, only some data existed about the …
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Synthesis and Characterization of Chalcogenide Perovskites
… perovskites are generally sulfur and selenium compounds which contain a 3D network of corner-sharing octahedra. Not until 2015 was this material class recognized as being suitable for any application. Their strong light absorption in the visible to near-IR wavelengths makes them of …
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Exploring the Synthesis, Structure, and Reactivity of Phosphorus-Chalcogen Heterocycles
… Lewis acids and bases, and again linking these compounds to the monomeric phosphinidene chalcogenides. Chapter 5 introduces the idea of combining two different low-coordinate phosphorus compounds (both generated from their parent dimer heterocycles) to generate a new heterocycle containing …
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Selenotrisulfide Derivative Of Alpha-lipoic Acid: Evaluation In A Cell Culture Model For Potential Use As A Topical Antioxidant
Selenium is a required micronutrient in mammalian cells. It is incorporated in the form of selenocysteine into selenoenzymes such as glutathione peroxidase and thioredoxin reductase, and is absolutely required for activity. Thioredoxin reductase is necessary for reduction of oxidized thioredoxin …
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Reactions of directly related tellurium and selenium heterocycic compunds with triiron dodecacarbonyl
The reactions of directly related tellurium and selenium heterocyclic compounds with triiron dodecacarbonyl are described. The reaction of 2-telluraphthalide, C8H8OTe with [Fe3(CO)12 gave [Fe{C6H4(CH2)Te}(CO)3]2, (1). An iron atom has inserted into the telluracyclic ring, and it is probable that …