Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Secreted glycoproteins"”.
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MS-Based Chemical Proteomics Studies of Extracellular Glycoproteins: Identification, Quantification, and Dynamics
… proteins, including cell-surface and secreted proteins, play crucial roles in cell-cell communication, cell-matrix interactions, and the regulation of most extracellular biological processes. The majority of these proteins, if not all, are glycosylated, which affects their functions, …
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Bead Based Peptidyl Libraries for the Selective Recognition of Glycoproteins, Differentiation of Carcinogenic Cell Types, and Determination of Enzyme Substrate Specificity
… glycosylation of integral cell membrane and secreted glycoproteins is a hallmark of carcinogenesis and presents a unique opportunity to detect cancer at its earliest stages, when it is most treatable. Work towards developing boronic acid functionalized bead based peptidyl synthetic lectins …
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Regulation of Neuronal Polarity by Wnt Signaling
Wnts are highly conserved secreted glycoproteins that function in many developmental processes. Cell surface receptors, including the Frizzleds (Fz), ROR, and RYK families of proteins, bind Wnts to activate a number of downstream pathways. Wnts act redundantly to regulate the anteroposterior …
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Mechanism of Action of Antiestrogens in Breast Cancer and Uterine Cells (Estrogen Receptor)
… the production of several estrogen-stimulated secreted glycoproteins of M(,r) 32,000, M(,r) 160,000, and M(,r) 52,000 from MCF-7 cells and also to stimulate production of a specific secreted glycoprotein of M(,r) 37,000 that is estrogen-inhibited. These proteins may be useful in studying the …
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In vitro Expression of Human Zona Pellucida Protein 3
… limiting molecular weight cut off at 30 kDa. The secreted glycoproteins were identified by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) with silver staining, Western blot analysis using a specific anti-ZP3 antibody, and by a metabolic labelling study using …
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Investigating the evolution and function of Wnt ligands
Wnt genes encode secreted glycoproteins which play an important role in development of all animals. Overall, thirteen subfamilies of Wnt ligands are present and all of them can already be found in the most basal metazoans. The importance of this large gene family and its evolutionary conservation …