Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Secondary envelopment"”.
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Glycoprotein M and ESCRT in herpes simplex virus type 1 assembly
… capsids in the cytoplasm, a process termed secondary envelopment. This process involves the coordination of numerous viral and cellular proteins and results in double-membrane structures with enveloped virions contained within cellular vesicles. Mature viruses are then released through the …
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Structural and biochemical characterisation of pUL7 and pUL51, conserved tegument proteins required for efficient herpesvirus assembly
… acquire a lipid envelope in a process called secondary envelopment. Herpes simplex virus (HSV)-1 proteins pUL7 and pUL51 form a complex that is involved in secondary envelopment, although their molecular function is not well understood. Neither pUL7 nor pUL51 share appreciable sequence-level …
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The role of heterochromatin markers in lytic human herpesvirus egress and maturation
… through acquisition of tegument proteins and secondary envelopment, and finally bud out of the host cell. The virus must contend with components of the host nucleus to replicate, including the host chromatin. Chromatin consists of DNA, RNA, and proteins that maintain the DNA structure. Host …
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Investigating the structure and function of HSV-1 tegument proteins: UL7 and UL51
… indicative of a defect in tegumentation and/or secondary envelopment. Similar phenotypes have been observed upon deletion of homologous proteins in pseudorabies virus and human cytomegalovirus, suggesting a conserved role for these proteins. This thesis presents evidence for the formation of a …
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Studies of viral and cellular proteins involved in herpes simplex virus type-1 egress
… of cells after egress. In the context of HSV-1 envelopment and egress glycoprotein E (gE), which forms a heterodimeric complex with gI (gE/gI), is known to be important. The gE/gI complex has been shown to interact with many tegument proteins and have a redundant role in secondary envelopment. …