Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"SecYEG"”.
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In vitro-Untersuchungen zum Sekretionsmechanismus der beta-Lactamase in Escherichia coli
… Translokation der Proteine durch das SecYEG-Translokon erfolgt in Abhängigkeit von SecA. <br>2. Das bakterielle signal recognition particle (SRP) und sein Rezeptor FtsY vermitteln die kotranslationale Zielsteuerung und Integration polytoper Innenmembranproteine an bzw. in das …
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In vitro studies on the SecA involvement in the assembly of an integral membrane protein with large hydrophilic domain
… of inner membrane proteins takes place via the SecYEG-translocon. The targeting pathways of secretory and membrane proteins to the SecYEG translocon however, are different. Integral membrane proteins are co-translationally targeted by signal recognition particle (SRP) and its receptor FtsY, …
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Single-molecule visualization of conformational changes in the SecA ATPase
… are pushed across the membrane, via the SecYEG channel, by the SecA ATPase. Relatively little is understood of how SecA couples ATP hydrolysis to polypeptide translocation. X-ray crystallography and many biochemical studies support a model in which the two-helix finger (2HF) of SecA …
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In vitro-Untersuchungen zum Sekretionsmechanismus von Pathogenitätsfaktoren mit einer N-terminalen Extension in Escherichia coli
… Translokation der Proteine durch das SecYEG-Translokon wird von SecA energetisiert. <br>2. Das bakterielle signal recognition particle (SRP) und sein Rezeptor FtsY vermitteln sowohl die co-translationale Zielsteuerung polytoper Innenmembranproteine an, als auch ihre Integration in das …
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A study of SecA : the motor of the bacterial secretion system by site-directed spin labeling and EPR
… and the membrane-embedded translocase SecYEG. Functional studies implied that some of these interactions occurred simultaneously. However, little is known about the details of these binding sites, and it was not clear to what extent SecA interacted with these diverse ligands at …
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Construction of an efficient secretion system for recombinant proteins in Bacillus subtilis
… channel translocon complex composed of the SecYEG proteins. Based on the known characteristics of both pathways, the goal of this PhD project was to construct an efficient secretion system for recombinant proteins in Bacillus subtilis using an a-amylase as a reporter enzyme, which is …
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Untersuchungen zum Integrations- und Translokationsmodus des Sec-Translokons in Escherichia coli
Das Sec-Translokon der bakteriellen Innenmembran katalysiert sowohl die Translokation sekretorischer Proteine als auch die Integration von Membranproteinen. Die Translokasefunktion erfordert die vektorielle Oeffnung der Translokationspore zur periplasmatischen Seite hin, waehrend die …