Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Sec18"”.
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The regulation of yeast homotypic vacuole fusion by phosphatidic acid and diacylglycerol
… SNAREs are activated by their co-chaperones Sec18 (mammalian NSF) and Sec17 (mammalian α-SNAP) in an ATP dependent priming stage. Tethering first brings two fusing compartments into contact with each other via interactions between the Rab GTPase Ypt7 and its effector HOPS complex. Once …
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Molecular analysis of vesicle biogenesis during autophagy
… autophagosomes was dubious, since neither NSF / Sec18 nor t-SNARES are required. Therefore a novel membrane fusion machinery requiring the Atg proteins has been proposed. In contrast this work supports the function of the previously excluded AAA+ ATPase Cdc48 in autophagic membrane fusion events.
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Lipid composition and membrane physical parameters regulate priming and SNARE function in yeast vacuole membrane fusion
… acid serves to bind a key AAA+ family ATPase, Sec18p that effects priming in yeast vacuolar membrane fusion. The yeast PA phosphatase Pah1p alters the ratio of PA to DAG on the membrane during priming and serves to recruit Sec18p to the cis-SNARE complexes at the site of priming. The second …