Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Sdf-1/Cxcl12"”.
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Die Bedeutung der Interaktion des Chemokins SDF-1 (CXCL12) mit CXCR4-Chemokinrezeptoren auf Leukämiezellen von Patienten mit Akuter Myeloischer Leukämie
KM - Stromazellen regulieren die Entwicklung und Proliferation HSC innerhalb des KM - Mikromilieus. Die AML stellt eine Neoplasie unreifer hämatopoetischer Zellen dar, durch die Verdrängung der gesunden Hämatopoese durch Blasten sind Teile des klinischen Erscheinungsbilds <br> der Erkrankung zu …
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Stat3 Controls The Neutrophil Migratory Response to Cxcr2 and Its Ligand Mip-2 (Cxcl2)
… neutrophil mobilization, in contrast to SDF-1 (Cxcl12), which contributes to neutrophil retention in the bone marrow, requiring downregulation to promote neutrophil release. Using a murine model with conditional STAT3 deletion in bone marrow, we demonstrate that STAT3 regulates …
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Tumor Angiogenesis is all Tied up in Tie2-Expressing Macrophages
… well. This along with the increases in Ang-2 and SDF-1/CXCL12 concentrations in M-CSF-treated tumors suggests a role for M-CSF in the recruitment of TEMs. These studies highlight role of TEMs specifically, and not total F4/80 macrophages, in tumor growth, angiogenesis and progression.
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The Role of miR-126/126* in Microenvironmental Regulation of Cancer Metastasis
… of stromal cell-derived factor-1 alpha (Sdf-1α, also known as Cxcl12), and indirectly suppress the expression of chemokine (C-C motif) ligand 2 (Ccl2) by the cancer cells within the tumour mass in an Sdf-1α-dependent manner. In addition, in contrast with the majority of reports which have …