Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Scribble"”.
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SCRIBBLE: A POTENTIAL DUAL KINASE INHIBITOR
… yeast two-hybrid assays using ERK6 as bait, and Scribble was identified as a binding partner. Scribble contains 16 LRR domains and four PDZ domains. We performed immunoprecipitation (IP) assays and discovered ERK2 as another binding partner. Surprisingly, no interaction was observed with the …
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Involvement of Scribble protein in breast cancer invasion and metastasis
… of cancer cells is the loss of cell polarity. Scribble is a cell polarity protein with an unknown mechanism for its role in tumour suppression. Changes in the phosphorylation pattern of four serine sites at the C-terminal of scribble, implicate scribble in breast cancer invasion and metastasis. …
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Cell Polarity Regulates Organ Growth Through The Hippo Pathway
… Cells mutant for the basolateral determinant <em>scribble </em>overproliferate and can form neoplastic tumors. Interestingly, <em>scribble </em>mutant clones that arise in wild-type tissues are eliminated and therefore do not manifest their tumorigenic potential. However, the mechanisms by which …
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Fantasia on a Theme of Purpose: Using a Music-Guided Scribble Technique to Support Meaning-Making in Older Adult Retiree Musicians
… how music-guided art-making incorporating the scribble technique could support a sense of purpose among older adult retiree musicians. In an art-based intervention that collected art and interview data, participants responded to self-selected music with a variety of fluid and resistive drawing …
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Interactive Part Selection for Mesh and Point Models Using Hierarchical Graph-cut Partitioning
… mesh and point set surface models that combines scribble-based selection methods with hierarchically accelerated graph-cut segmentation. Using graph-cut segmentation to determine optimal intuitive part boundaries enables easy part selection on complex geometries and allows for a simple, …
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Investigating the mechanisms of cell competition in mammals using in vitro systems
… system, in which wild-type MDCK cells eliminate scribble-deficient cells, and I have also developed a novel cell culture system to model mammalian competition. My work contributed to the discovery that scribble-deficient cells are eliminated not by biochemical exchange among cells, but by …
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Art Based Communication for Individuals with Dissociative Spectrum Disorders
… completed a body outline drawing, a bilateral scribble (BLS), and a self-report on their artwork. The results showed significant pretest to posttest increases in self-awareness for each of the groups after completing the art intervention. No significant differences were found between groups …
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Advanced Radar Sounder Data Analysis Methods under Limited labeled Data Constraints
… archives. The second contribution introduces scribble driven semi-supervised semantic segmentation using an efficient u2net architecture. First, we develop a parameterefficient u2net architecture that achieves high accuracy even with limited labeled data. Building on this, we introduced a …
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Normative Study of Art by Children on Autism Spectrum Age 2-14 Years: A Pilot Study
… Ten of these participants created strictly scribble drawings and 8 created pictorial drawings which were rated according to the FEATS. Results indicate that children with ASD trend toward lower scores on the level of integration of image and the use of color in the drawings when compared to …
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Learning Object Detection with Weak Supervision
… RGB-D inputs (i.e., images and depth maps) with scribble-based weak supervision. This thesis explores annotator-friendly scribble annotations for training models. A dual-modal edge-guided network and a prediction consistency training method are developed to fully take advantage of the …
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Motherhood, performance, and mommy blogs: the political power of maternal online rhetoric
"If you define writing as any kind of scribble, any kind of trying to mark on the world," Gloria Anzaldúa says in an interview with Andrea Lundsford, "And, some of us want to take those marks that are already inscribed in the world and redo them." Language - and thus, writing - has the power to …
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Re:Re:Re: Supermodern Fashion and Fashion Design in the 21st century
… unsustainable. This work used Damien Newman’s scribble method in combination with sketching and critical making, using artifacts and research to analyse various interpretations of supermodernity.
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Investigating WNT signalling in the lung
… changes in the protein expression of Vangl2 and Scribble. Meanwhile, studies on human lung cell lines suggested that WNT4, ATMIN, WNT11, and PKD2 could be potential regulators of lung development, particularly in branching morphogenesis, alveolar development, and angiogenesis. These findings …
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The mechanisms underlying mechanical cell competition and leader cell migration in mammalian epithelia
… this system, silencing of the tumour suppressor scribble (scribKD) results in a ‘loser’ phenotype whereby scribKD cells are specifically eliminated from the monolayer by surrounding wild-type cells. More specifically, scribKD cells are compacted into tight clones through activation of a directed, …