Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 741 for “"Sclerosis"”.
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Disseminated sclerosis
… with special reference to subacute combined sclerosis. 12 of the cases came under my personal observation, for the notes of the remaining cases, I am indebted to W. B. Warrington, F.R.C.P.
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Metabolomic characterization of Multiple Sclerosis
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system with a strong autoimmune component. MS is the most common cause of non-traumatic acquired neurological disability in young adults with a particularly high incidence in Sardinia. Several aspects still represent …
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Parental Stress In Tuberous Sclerosis Complex
<p>Tuberous Sclerosis Complex (TSC) is a multi-systemic genetic disorder with great clinical variability. As the needs of one child with TSC may vastly differ from another, parenting demands may similarly differ. Characterizing parental stress, or emotional maladaptation arising from parenting …
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Profiling neuroinflammation in amyotrophic lateral sclerosis
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease primarily characterised by progressive loss of motor neurons. ALS is highly heterogeneous and exists on a clinical and pathogenetic spectrum with frontotemporal dementia (FTD); those anywhere on this spectrum are said to …
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Imaging and therapy in multiple sclerosis
Multiple sclerosis (MS) is a common, debilitating autoimmune disorder of the central nervous system (CNS). The most visible element of MS pathology is white matter (WM) lesions. However, extra-lesional abnormalities are recognised and appear most marked at the outer (subpial) brain surfaces at …
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Tobacco Smoke Exposure and Pediatric Multiple Sclerosis
Introduction: Multiple sclerosis (MS) is a chronic inflammatory disease which affects approximately 2.5 million people worldwide, including approximately 7,000 children. The etiology of MS is unclear, although researchers generally agree that both environmental and genetic factors are involved. It …
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Adipocytes and Innate Immunity In Systemic Sclerosis
<p>Systemic sclerosis (SSc; scleroderma) is a chronic systemic autoimmune and connective tissue disorder characterized by vasculopathy, autoimmune phenomena, and widespread fibrosis. Skin thickening and tightening is the cardinal feature of SSc and is responsible, in part, for the considerable …
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Marking the immune system in systemic sclerosis
Contains fulltext : 141096.pdf (Publisher’s version ) (Open Access)
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Deciphering the genetic background of Systemic Sclerosis
Contains fulltext : 99157.pdf (Publisher’s version ) (Open Access)
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Gait variability in persons with multiple sclerosis
… gait variability in people with multiple sclerosis (MS), which is a neurological disease that can result in significant walking impairment. Gait variability, i.e. fluctuations in the mechanics and kinematics of steps during walking, has been associated with motor control function, …
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Human herpesvirus 6 in multiple sclerosis and encephalitis
… system (CNS) such as encephalitis and multiple sclerosis (MS). The present studies were aimed to elucidate the role of HHV-6 and its two variants in neurological infections. Special attention was given to study the possible role of HHV-6 in the pathogenesis of MS. We studied the expression of …
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Engagement in occupations in persons with Multiple Sclerosis
… in occupations in persons with Multiple Sclerosis (MS) in order to develop client-centred occupational therapy and rehabilitation. In study I, observations of the performance of self-care and household occupations were pursued in 44 participants, and study II identified self-perceived …
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Lipid Metabolism in Mild to Moderate Multiple Sclerosis
Objective: The purpose of this study was to assess lipid metabolism in persons with mild to moderate MS through an examination of dyslipidemia. Plasma concentrations of PCSK9 and its potential correlation between LDL-C. Methods: A case-controlled design was used to access potential differences in …
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New Therapeutic Strategies for Amyotrophic Lateral Sclerosis Treatment
Amyotrophic lateral sclerosis (ALS) is characterized by progressive dysfunction and degeneration of motor neurons in cerebral cortex, brain stem and spinal cord. Degeneration of motor neurons causes muscle weakness and respiratory paralysis, leading to decease of ALS patients. Approximately 10% of …
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Characterization of Peripherin Isoforms in Amyotrophic Lateral Sclerosis
… neurodegenerative disease amyotrophic lateral sclerosis (ALS). Interestingly, peripherin overexpressing transgenic mice succumb to motor neuron disease with pathological hallmarks reminiscent of those found in ALS. Pathological peripherin abnormalities occur with high frequency in both familial …
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Vliv psychické zátěže na rozvoj onemocnění sclerosis multiplex
… práce Vliv psychické zátěže na rozvoj onemocnění sclerosis multiplex jsem si vybrala na základě svého zájmu o obor neurologie. S ohledem na nutnost preventivní tématiky jsem ve spolupráci s MUDr. Medovou vybrala toto téma, neboť v minulosti vyšlo již několik prací zabývajících se touto …
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