Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Sciatic Nerve Ligation"”.
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THE ROLE OF SKELETAL MUSCLE-SYNTHESIZED BRAIN DERIVED NEUROTROPHIC FACTOR IN THE MAINTENANCE OF MOTOR NEURON MITOCHONDRIAL POPULATIONS
… groups underwent a gastrocnemius harvest or a sciatic nerve ligation protocol prior to sacrifice. In combination with MitoTracker™ injections, we used immunohistochemical labeling to target the mitochondrial translocase of outer membrane, TOM20. We used immunolabeling to further delineate …
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THE ROLE OF SKELETAL MUSCLE-SYNTHESIZED BRAIN-DERIVED NEUROTROPHIC FACTOR IN RETROGRADE TRANSPORT ALONG MOTORNEURON AXONS
… deficient mice, but not in 30d animals. Sciatic nerve ligation experiments show significantly less accumulation of NF-H-P and the motor associated protein, dynactin 1, immediately distal to the ligation site in muscle-BDNF deficient mice at 120d, but not at 30d. These results indicate …
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Investigating the Contribution of the Inflammasome to Persistent Pain States
… condition, occurs as a consequence of nerve injury with symptoms such as spontaneous pain, hyperalgesia, and allodynia commonly reported. In animal models of peripheral nerve injury, there is accumulation and proliferation of microglial cells in the injured spinal cord and macrophages …
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CHARACTERIZATION OF THE ROLES OF MUSCLE-SYNTHESIZED BRAIN-DERIVED NEUROTROPHIC FACTOR AND PRESYNAPTIC TYROSINE RECEPTOR KINASE B IN MOTOR NEURON AXONAL TRANSPORT
… dynactin, and JIP3 were evaluated following sciatic nerve ligations to assess the functionality of axonal transport mechanisms in mice lacking muscle-synthesized BDNF. Pre- and postsynaptic TrkB activation was significantly reduced, and both anterograde and retrograde transport were …