Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Schizophrenia--Pathophysiology"”.
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Exploring the role of Rapgef6 in neuropsychiatric disorders
Schizophrenia is highly heritable yet there are few confirmed, causal mutations. In human genetic studies, we discovered CNVs impacting RAPGEF6 and RAPGEF2. Behavioral analysis of a mouse modeling Rapgef6 deletion determined that amygdala function was the most impaired behavioral domain as measured …
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Application and integration of bioinformatic strategies towards central and peripheral proteomic profiling for diagnosis and drug discovery in schizophrenia
Proteomic profiling studies of schizophrenia have the potential to shed further light on this debilitating and poorly understood condition which affects up to 1% of the world’s population. However, recent studies suggest that the field of proteomics in general has been hindered by poor application …
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Frequency specific deficits in schizophrenia
… deficits and frequency specific deficits in schizophrenia. Coherence between different lobes of the brain from task related data at different frequency bands was investigated in patients with Schizophrenia (SP) and Healthy Normal Volunteers (HNV). The task was aimed to study the neural …
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Anatomical and Functional Characterization of the Ventral Hippocampus in a Rodent Model of Schizophrenia Neuropathology
Schizophrenia is a debilitating, life-long illness with a still-unknown, complex etiology and, currently, no cure. Many studies have implicated the hippocampus and the parahippocampal region as a place of both primary pathology in the disease and as regions correlated to symptom severity. To better …