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Showing 1 to 1 of 1 for “"Saturation mutagenesi"”.
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A PERTURB-SEQ SATURATION MUTAGENESIS APPROACH TO DISSECT THE MOLECULAR BASES OF GENETIC DISEASES
… of patients. To address this point, MITEseq (Mutagenesis by Integrated TilEs) is a novel saturation mutagenesis technique that allows us to quickly test thousands of potentially pathogenic protein variants in a single high throughput biological assay. As proof of principle, we decided to apply …