Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"Sample-to-answer"”.
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From Sample to Answer: Innovations in sample processing and CRISPR-based diagnostics for enhanced clinical translation and field deployment
… testing capacity is currently insufficient to effectively respond to emerging infectious disease threats, which has fueled the spread of Lassa, Ebola, SARS-CoV-2, and Zika virus in recent years. Globally, this diagnostic gap is particularly pronounced at the primary care or community level, …
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Development of a High Sensitivity, Multiplex Vertical Flow Immunoassay System for the Detection of Biothreat Agents
… contaminant materials and individuals to safeguard public health. The historical reliance on centralized laboratory networks, with their delayed turnaround times, has motivated a shift toward developing decentralized systems that enable early detection and expedite appropriate …
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Isothermal Nucleic Acid Assays for the Detection of HIV Drug Resistance and Sickle Cell Disease in Low-Resource Settings
… in these settings has made it difficult to implement effective strategies to differentiate ARV therapy from true instances of drug resistance. 90% of HIV drug resistance is caused by four specific single-nucleotide polymorphisms (SNPs). Sickle cell disease (SCD) is another disease of …
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Low-Cost Electronic Microfluidics for Multiplexed Point-of-Care Biomarker Detection
… as they can aid in disease detection, monitoring, and treatment, and even inform public policy. However, while qualitative (yes/no) PoC sensors are abundant (i.e. pregnancy tests, rapid COVID19 tests), low-cost, automated, quantitative PoC platforms are limited. Yet, given the importance of …
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Design and Application of Hollow Silica Microspheres for Density-based Bioseparations
Challenges to the detection of low-abundance biological analytes from complex mixtures, such as biological fluids and food extracts, still exist and are critical for the management of infectious diseases like influenza and gastroenteritis. Typically, analytes must be separated and concentrated from …
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Design and application of hollow silica microspheres for density-based bioseparations
Challenges to the detection of low-abundance biological analytes from complex mixtures, such as biological fluids and food extracts, still exist and are critical for the management of infectious diseases like influenza and gastroenteritis. Typically, analytes must be separated and concentrated from …
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Accelerated Sepsis Diagnosis by Seamless Integration of Nucleic Acid Purification and Detection
… sepsis diagnostic methods there is an unsatisfactory trade-off between the assay time and the specificity of the derived diagnostic information. Although the present qPCR-based test is more specific than biomarker detection and faster than culturing, its 6 ~ 10 hr turnaround remains suboptimal …