Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Sample Pretreatment"”.
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A PDMS Sample Pretreatment Device for the Optimization of Electrokinetic Manipulations of Blood Serum
This project encompasses the design of a pretreatment protocol for blood serum and adaption of that protocol to a microfluidic environment in order to optimize key sample characteristics, namely pH, conductivity, and viscosity, to enable on-chip electrokinetic separations. The two major parts of …
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A study of column switching liquid chromatography in drug analysis.
Drug analysis methods and the sample pretreatment of biological fluids are reviewed. A survey of column switching liquid chromatography techniques revealed the range of column dimensions, the frequency of prior sample pretreatment steps and small injection volumes used and the varied longevity of …
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POLYMERIC MEMBRANE DEVICES AND AUTOMATION - DESIGNS FOR INNOVATIVE STUDY IN MICROSCALE ANALYTICAL TECHNIQUES FOR ENVIRONMENTAL ANALYSIS
… presents the development of miniaturized sample preparation techniques and procedures for environmental analysis. Various applications of the developed techniques are also demonstrated. The miniaturized sample preparation approaches under study comprise of electromembrane extraction (EME), …
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Towards a microfluidic disease detection deviced based on cellular adhesion differences
… age, and cell type with the minimum amount of sample pretreatment. This project addresses this need by developing microfluidic devices that exploit the adhesion differences between cell states and cell types to rapidly count cells of different types without the need for labels. There are two …
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Portable blood plasma separation for point of care diagnostics
… of microfluidic sensors is the biological sample pretreatment steps that are manually performed prior to on-chip loading and sensing. This issue is especially prominent for human blood, which contains about a billion cells in one milliliter total volume. These blood cells can rupture, clog …
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Polymer Microchips for Capillary Electrophoresis and Electric Field Gradient Focusing of Biomolecules
… with hydrogel structures, for example in sample pretreatment.</p>
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Utilización combinada de técnicas analíticas y quimiométricas en lipidómica orientadas al descubrimiento de biomarcadores asociados a alteraciones en el metabolismo de lípidos
… be taken in the pre-analytical stages and the pretreatment of samples that are carried out in clinical laboratories in the order to show how these procedures can condition and alter the metabolites of biological samples. For this reason, all possible parameters or variables involved both in the …
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Enzyme-Linked Electrochemical Detection of Urinary Sarcosine
… chronocoulometric sarcosine detection in static samples of PBS and artificial urine matrix (AUM). However, initial EnzL-ECBS designs suffered severe sensitivity limitations. Characterisation studies demonstrated that sarcosine detection was obstructed by the impact of several AUM components …
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Engineering programmable nucleases for in vivo and in vitro applications
… and E gene of the SARS-CoV-2 virus in saliva samples spiked with the virus, with a limit of detection (LoD) of 0.44 copies/μL and 1.09 copies/μL, respectively, within 30 minutes. Furthermore, the SPOT system successfully analyzed 104 clinical saliva samples, exhibiting a sensitivity of 93.3% …
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Chemical Micro Preconcentrators Development for Micro Gas Chromatography Systems
… (µPC) extracts the target analytes from the sample matrix, concentrates them, and injects them into the separation column for analysis. This work resulted in the development of silicon-glass bonded chips consisting of 7 mm x 7 mm x 0.38 mm multiport cavity with thousands of embedded 3D …
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Label-free carbon nanotube sensors for glycan and protein detection
… and microarray methods, are limited by sample pretreatment and quantitative accuracy. Microarrayed platforms can be improved with methods that better estimate kinetic parameters rather than simply reporting relative binding information. These quantitative glycan sensors are enabled by an …