Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 32 for “"Salmonella infection"”.
-
REGULATION AND EXPRESSION OF AMYLOID CURLI IN SALMONELLA INFECTION
… curli and form biofilms in the gut during infection due to the contrasting conditions between life outside versus inside the host. However, there is indirect evidence in support of curli expression in both humans and mice during infection. Furthermore, bacterial infections are important …
-
Experimental Approaches to Understand and Control Salmonella Infection in Poultry
<p>Salmonella is a major foodborne pathogen around the world and chickens are the major reservoir to transmit Salmonella into the human food chain. For decreasing the infection of Salmonella, we developed six attenuated live vaccines based on Salmonella Enteritidis (SE) and Typhimurium (ST) for …
-
Intercellular production of Hydrogen peroxide in Solanum lycopersicum: an immune response to Salmonella infection
… of deaths per year recorded. Outbreaks of Salmonella have been reported from a multitude of vegetables such as lettuce, spinach and tomatoes. Many of these outbreaks are the result of infection via non-typhoid Salmonella species such as Salmonella enterica sv. Typhimurium. The ecology of …
-
Early protection against Salmonella infection in chickens by modification of the initial host-pathogen interactions
Sinds halfweg de tachtiger jaren is Salmonella Enteritidis doorgebroken als een belangrijke voedselinfectie bij de mens. In België worden jaarlijks meer dan 10.000 humane Salmonella Enteritidis isolaten gerapporteerd, meestal verbonden met de consumptie van pluimveeproducten. Infectie van pluimvee …
-
Effects of Habitat on Physiology and Infection in Aquatic Turtles
Finally, Salmonella infections in slider turtles were not significantly affected by the host or habitat characteristics measured in this study. No turtles out of 100 were shedding Salmonella. Dissections of 73 turtles, however, revealed that turtles in the region had a moderate prevalence (11%) of …
-
Dynamics of the innate immune response to infection: a mathematical modelling approach
… system plays a vital role in the control of infection, but many aspects of its behaviour are not fully understood. In this dissertation, I use mathematical modelling approaches to elucidate two linked processes which are key to the innate immune response to Salmonella infection. First, I …
-
Regulation of gene expression in macrophage immune response
… interferon- gamma (IFNɣ) treatment (18h), Salmonella infection (5h), and IFNγ treatment followed by Salmonella infection. We also measured chromatin accessibility with ATAC-seq in 31-42 individuals in the same four conditions. We detected gene expression QTLs (eQTLs) for 4326 genes, over …
-
Mode of Entry and Survival of Salmonella Enterica Serovar Typhimurium in Trophoblast Cells
Salmonella enterica species are intracellular bacteria causative agents of gastroenteritis and typhoid fever in humans. Pregnancy poses an increased risk of severe Salmonellosis in many mammalian species contributing to miscarriage and/or maternal illness. Previous studies indicated that Salmonella …
-
Comparison of Potential Salmonella Portals of Entry and Tissue Distribution Following Challenge of Poultry
… route may be a viable portal of entry for Salmonella and could explain some clinical impressions of relatively low-dose infectivity under field conditions in relation to the requisite high oral challenge dose that is typically required for infection of poultry through the oral route in …
-
Multi-omics investigation of interactions between persistent bacteria and Salmonella in the inflamed gut
Salmonella is a globally relevant enteric pathogen responsible for numerous outbreaks and debilitating illness yearly. Expansive tropism allows Salmonella to find bastion in zoonotic reservoirs including prominent food animals. Continued prophylactic antibiotic use in livestock and therapeutic …
-
Effect of a Fermented Yeast Product on the Gastrointestinal Tract Microbial Diversity of Weaned Pigs Challenged With Salmonella Enterica Typhimurium Dt104
… before, during and after an oral challenge with Salmonella. Pigs (n= 40) were weaned at 21 d of age, blocked by body weight (BW) and assigned in a 2Ã 2 factorial arrangement consisting of diet (control or 0.2% XPC) and inoculation (broth or Salmonella). Diet had no effect on pig growth …
-
1,000 ancient genomes uncover 10,000 years of natural selection in Europe
… selection at a locus that confers resistance to Salmonella infection at a time when ancient Salmonella have been shown to adapt to human hosts. Neolithic period candidates are also related to body weight and insulin secretion, suggesting adaptation to a primarily starch-based diet; in contrast, …
-
Immuno-modulatory functions of CD1d-restricted natural killer T cells
… produced IFN-gamma during the early phase of Salmonella-infection. Additionally, the infection was observed to skew the cytokine production profile of the NKT cells toward a protective IFN-gamma-dominated profile.
-
Extracytoplasmic stress response systems in S. Typhimurium
Salmonella species can cause wide-ranging disease from mild food-poisoning enteritis to a systemic, sometimes fatal typhoid infection. These bacteria have evolved to survive in different environments within and outside the host and do so through the regulation of differential gene expression …
-
Real-Time Bioluminescence Imaging Of Salmonella-Neoplastic Cell Interactions
Salmonella Typhimurium is a Gram-negative bacterial pathogen and a common cause of gastroenteritis in humans. The organism utilizes a multitude of well-studied virulence factors to invade and replicate in host intestinal epithelial cells and macrophages. Interestingly, Salmonella is also capable of …
-
Genome-scale metabolic modelling of Salmonella and Lactobacillus species
Salmonella Typhimurium is a major cause of morbidity and mortality in humans. It is also a commonly used model organism for intracellular Gram negative pathogens, a group of bacteria that is becoming increasingly resistant to available antibiotics. Systemic Salmonella infection involves …
-
Colonocyte-Derived Lactate Promotes Enterobacteriaceae Fitness During Non-Infectious Colitis
… after perturbances induced by helminth infection, antibiotics, and non-infectious colitis. We specifically probe the contribution of metabolism by members of the Enterobacteriaceae family of bacteria, a group known to commonly outgrow during intestinal inflammation. In the example of …
-
Impact of exogenous factors on amino acid digestibility in non-ruminants
… (EAAL) when pigs were challenged orally with Salmonella enterica serovar Typhimurium. Nursery pigs (n = 48, 17.9 ± 0.5 kg) were randomly assigned to a 2 Ã 2 factorial arrangement consisting of two diets (control or N-free) and inoculation (sterile broth or 9.8 Ã 10^9 CFU of Salmonella). …
-
The Structural and Biochemical Characterization of Salmonella Host Specificity Determinant Gifsy-2 Gene E
<p>Salmonella enterica continues to be a significant public health concern, causing an estimated 93.8 million cases of non-typhoidal salmonellosis and 21 million cases of typhoid fever worldwide each year. There are thousands of Salmonella enterica serovars, some with a very specific host set, and …
-
Gene expression during the host-bacteria interaction
… replication. Changes in gene expression during infection are thus the net result of these competing goals, the balance of which can ultimately determine the infection outcome. While the transcriptional response to bacterial infection is well studied, the analysis of gene expression is incomplete …
Page 1 of 2