Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 196 for “"Salmonella Typhimurium"”.
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Genetic duplication in Salmonella typhimurium
A gene duplication occurs in Salmonella typhimurium which involves about 30% of the genome. The frequency of formation and loss of this duplication was determined in a Rec.A⁻ strain and a PolA⁻ strain and compared to that of a RecA⁺, PolA⁺ strain. The frequency of formation was found to be reduced …
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Oxygen Regulated Genes in Salmonella Typhimurium
… leucine and casamino acids, showed that S. typhimurium produced propionate from threonine.
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Inflammasome signalling during Salmonella Typhimurium infection
… immune response. Gram-negative bacteria such as Salmonella enterica serovar Typhimurium express a range of bacterial PAMPs recognised by Toll-like receptors (TLRs) including lipopolysaccharides (LPS) recognised by TLR-4 and lipoproteins by TLR-2. The activation of TLRs results in activation of …
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The Mechanism of Aerotaxis in SALMONELLA TYPHIMURIUM
… relationship to other chemotaxis pathways in <em>Salmonella typhimurium</em> was explored with the aid of two new assays which imposed an oxygen gradient independently of bacterial respiration. In the spatial assay, bacteria accumulated at the mouth of an oxygen-filled capillary. In the temporal …
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Antibody Response to Lipopolysaccharide of Salmonella Typhimurium
… mAbs in mice challenged with virulent S. typhimurium. Therefore, a subtle modification of O-Ag such as acetylation has a profound effect on the host immune response.
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Gene Regulation of Tartrate Metabolism in Salmonella typhimurium
Salmonella Typhimurium (S. Tm) triggers an inflammatory response in the gut that favors the outgrowth of the pathogen over the resident microbiota. Early in S. Tm infection, oxidation of simple sugars by reactive nitrogen and oxygen species gives rise to L- and D-tartrate, which support fumarate …
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Interactions between salmonella typhimurium and human gut bacteria
Salmonella enterica subsp. enterica serovar Typhimurium is an important enteropathogen that causes human morbidity and mortality worldwide. It is essential to study the interaction between Salmonella and the gut bacteria to elucidate the elements that influence the ability of the pathogen to …
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A Multifaceted Approach to Study Salmonella Typhimurium Pathogenesis
To study Salmonella pathogenesis we used the IVET ( in vivo expression technology) system to select S. typhimurium genes that are specifically induced in the host during infection. This unique IVET selection was done in hopes of finding genes specifically induced in the aorta of BALB/c mice. In …
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A Characterization of Aspartyl Peptidases in Salmonella Typhimurium
… of the peptidases previously characterized from Salmonella typhimurium are capable of hydrolyzing aspartyl peptides. Peptidase E, an aspartyl specific dipeptidase, was the first member of a new family of peptide hydrolases that now includes peptidases from other proteobacteria and from two …
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Genetic dissection of proline transport by Salmonella typhimurium
… of substrate transport. Proline transport by Salmonella typhimurium is a good model system for studying the molecular mechanism of ion-driven transport systems. The putP gene encodes proline permease, a sodium/proline symport system. In order to identify the active site of proline permease, we …
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The role of wzz genes in Salmonella typhimurium virulence.
Salmonella is a genus of Gram-negative bacteria responsible for food-borne enteritis and systemic fever. Salmonellosis continues to be a serious health burden worldwide. Lipopolysaccharide (LPS) is the dominant lipid component of the outer membrane of Salmonella. LPS is composed of lipid A, an …
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Charakterisierung eines Typ III-Sekretionssystems für Virulenzproteine aus Salmonella typhimurium
… des Typ III-Sekretionssystems, kodiert von der Salmonella- Pathogenitätsinsel 2, wurden polyklonale Antikörper gegen rekombinante Proteine des Sekretionsapparates erzeugt. Zur Entfernung unspezifischer Bindungen wurden die polyklonalen Antiseren an eine CNBr-aktivierte Sepharose 4B, gekoppelt …
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Further characterisation of the envelope stress responses of Salmonella Typhimurium
Salmonella serovars are enteric pathogens of economic and clinical importance. The ability of Salmonella spp. to sense and adapt to exogenous stresses contributes towards infection severity and prevalence. The envelope stress responses promote survival within and between hosts by maintaining …
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Interaction of Salmonella typhimurium and Listeria monocytogenes with the murine host
… intestinal barrier. Many of these pathogens, eg Salmonella typhimurium and Shigella flexneri, use M cells, found only within the follicle associated epithelium (FAE) that overlies Peyer’s patches and other lymphoid follicles, to enter the host. This study is primarily an investigation into the …
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Fate of Salmonella Typhimurium in biofilms of drinking water distribution systems
The propensity of Salmonella to persist in water environments under unfavourable conditions is of concern as these water environments serve as contamination reservoirs. The role of contaminated water in the transmission of Salmonella in developing countries is largely unknown. The fate and …
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Isolation and Characterization of a Novel Motility Mutant in SALMONELLA TYPHIMURIUM
… isolated from mutagenized cultures of <em>S. typhimurium</em> was deficient in chemotaxis (Che<sup>-</sup> phenotype) in tryptone semisoft agar, but had random motility with a tumbling frequency (37%) similar to that of the parental strain, ST23 (39%). In spatial assays accumulation of BT40 …
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Salmonella Typhimurium infections in pigs: a closer look at the pathogenesis
… bij de mens wordt vaak veroorzaakt door Salmonella enterica subspecies enterica serovar Typhimurium (Salmonella Typhimurium). De ziekte veroorzaakt door deze bacterie is voornamelijk geassocieerd met het eten van varkensvlees. Varkens die geïnfecteerd zijn met Salmonella Typhimurium zijn …
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