Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 694 for “"Salmonella"”.
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Characterisation of the temperate bacteriophages of salmonella enterica and salmonella bongori
Salmonella is a major cause of enteric illness in both humans and animals. The ability of Salmonella isolates to cause disease in animals and humans encompasses a spectrum of host specificity and disease severity. In terms of evolution Salmonella isolates have remained relatively similar in terms …
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Characterising the immune response to Salmonella and Salmonella surface antigens during a systemic infection
Immunity to Salmonella enterica serovar Typhimurium (STm) is complex and requires both cell mediated and humoral immunity at different stages of infection. In infants in sub-Saharan Africa infection with non-typhoidal Salmonella (NTS), such as STm, can commonly cause fatal invasive disease. …
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Genomvariabilität bei lambdoiden Salmonella-Phagen
… Phagenpopulation aus Naturisolaten von Salmonella typhimurium wurde die Modulzusammensetzung innerhalb einer bestimmten Gruppe von Genen, der Lysisgenkassette, untersucht. Hierbei existiert prinzipiell ein großes Variationspotential, das jedoch in der Natur bei weitem nicht in dem Maße …
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Genetic duplication in Salmonella typhimurium
A gene duplication occurs in Salmonella typhimurium which involves about 30% of the genome. The frequency of formation and loss of this duplication was determined in a Rec.A⁻ strain and a PolA⁻ strain and compared to that of a RecA⁺, PolA⁺ strain. The frequency of formation was found to be reduced …
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Nachweis von Salmonella spp. bei Landschildkröten
… study an efficient procedure for detecting salmonellas in feces of tortoises should be established. First of all a survey of occurrence of salmonellas in reptiles and their importance for reptiles as well as for man is given. Next an appropriate incubation temperature for multiplying …
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Oxygen Regulated Genes in Salmonella Typhimurium
Studies on oxd-2 showed that it encodes a 42-kD protein which has acetate/propionate kinase activities. The cloned oxd-2 gene, under a foreign promoter, complemented an ackA (encoding an acetate kinase) mutation. Both Oxd-2 and AckA have a similar substrate range, and Oxd-2 has higher affinity for …
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Regulation of virulence in Salmonella enterica
Salmonella enterica serovar Typhimurium is a facultative intracellular pathogen, capable of causing disease in a variety of animal hosts. Both invasion of the host intestinal epithelial cells, and survival and replication in host macrophages are required for the successful establishment of the …
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Inflammasome signalling during Salmonella Typhimurium infection
… immune response. Gram-negative bacteria such as Salmonella enterica serovar Typhimurium express a range of bacterial PAMPs recognised by Toll-like receptors (TLRs) including lipopolysaccharides (LPS) recognised by TLR-4 and lipoproteins by TLR-2. The activation of TLRs results in activation of …
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Understanding small RNA-mediated post-transcriptional regulation of Salmonella pathogenicity island 1 activator HilA in Salmonella typhimurium
Salmonella Pathogenicity Island 1 (SPI1) encodes a Type-3 secretion system (T3SS) essential for Salmonella invasion of intestinal epithelial cells. Many environmental and regulatory signals control SPI1 gene expression, but in most cases, the molecular mechanisms remain unclear. Many regulatory …
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Ultraviolet Induction Properties of SALMONELLA POTSDAM Bacteriophages
<p>Three lysogenic strains of <em>Salmonella potsdam</em> were studied to determine whether or not they were inducible by ultraviolet light under certain conditions. The strains examined were SP3, SP4, and SP9. SP3 and SP4 contained a single prophage each and SP9 contained two prophages P9a and …
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The Mechanism of Aerotaxis in SALMONELLA TYPHIMURIUM
… relationship to other chemotaxis pathways in <em>Salmonella typhimurium</em> was explored with the aid of two new assays which imposed an oxygen gradient independently of bacterial respiration. In the spatial assay, bacteria accumulated at the mouth of an oxygen-filled capillary. In the temporal …
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Antibody Response to Lipopolysaccharide of Salmonella Typhimurium
This differential mAb recognition of O-Ag had a direct correlation with the differential level of protection mediated by individual mAbs in mice challenged with virulent S. typhimurium. Therefore, a subtle modification of O-Ag such as acetylation has a profound effect on the host immune response.
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Periplasmic determinants of virulence in Salmonella enterica
Salmonella enterica serovar Typhimurium is a facultative intracellular pathogen that is capable of causing systemic infection in mammals. Its normal course of infection brings this organism into the diverse environments of the stomach, the small intestine, the large intestine, and in the case of …
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Survival of Salmonella in the macrophage phagosome
Salmonella Typhimurium is a gram-negative facultative anaerobe bacterium capable of causing life threatening disease in humans. Transmitted via the fecal-oral route, S. Typhimurium infection typically results in self-limiting gastroenteritis. However, in immunocompromised patients, Salmonella can …
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Effector-driven actin reorganisation restricts Salmonella invasion.
… in the pathogenesis of enteric bacteria such as Salmonella is entering the host cell. To achieve this, Salmonella inject effector proteins into the cytosol of the cell and manipulate the actin cytoskeleton, driving pathogen entry. Two of the delivered effectors, namely SopE and SopE2, activate …
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Coordinated regulation of the flagellar, Salmonella pathogenicity island 1, and the type I fimbriae gene networks in Salmonella typhimurium
… from the cell. Using the food-borne pathogen, Salmonella, as a model organism, we try to investigate how cells encode strategies in networks to optimally control cellular behavior. Salmonella, on ingestion with contaminated food, swims in small intestine using propeller-like structures, …
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Gene Regulation of Tartrate Metabolism in Salmonella typhimurium
Salmonella Typhimurium (S. Tm) triggers an inflammatory response in the gut that favors the outgrowth of the pathogen over the resident microbiota. Early in S. Tm infection, oxidation of simple sugars by reactive nitrogen and oxygen species gives rise to L- and D-tartrate, which support fumarate …
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Interactions between salmonella typhimurium and human gut bacteria
Salmonella enterica subsp. enterica serovar Typhimurium is an important enteropathogen that causes human morbidity and mortality worldwide. It is essential to study the interaction between Salmonella and the gut bacteria to elucidate the elements that influence the ability of the pathogen to …
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