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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 831 for “"Saccharomyces cerevisiae"”.
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Ceramidsynthese in Saccharomyces cerevisiae
The work presented in this dissertation gave the following results: (i) Sequence homologous of the membrane proteins Lag1p and Dgt1p exist all over the kingdom of eucaryotes. All of them share a highly conserved motif with two hydrophilic residues within a transmembrane domain. A limited …
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Genome engineering in saccharomyces cerevisiae
… to the traditional petrochemical industry. Saccharomyces cerevisiae is one of the most widely used microbial cell factories, to produce ethanol as the first generation of biofuel. To enable this yeast as a producer for 1-butanol, which is a next-generation gasoline substitute, I discovered, …
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Synthetic sensing systems in Saccharomyces cerevisiae
The yeast Saccharomyces cerevisiae is a major chemical production platform in the biotechnological industry. It is also increasingly being used as a whole cell biosensor. One method of developing such whole cell biosensors in yeast is by exploiting its mating pathway, which is normally induced by …
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On Sulfur Sensing in Saccharomyces cerevisiae
… of sulfur-containing metabolites. In the yeast Saccharomyces cerevisiae, regulation of sulfur metabolism can be distilled down to the actions of two proteins; the F-box protein Met30, and the transcriptional coactivator Met4. Met30 belongs to the family of SCF (Skp1-Cul1-F-box protein) E3 …
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Das Dhh1 Protein aus Saccharomyces cerevisiae
Das Dhh1 Protein aus Saccharomyces cerevisiae ist aufgrund von acht hoch konservierten Aminosäure-Motiven als putative RNA Helikase klassifiziert. In S. pombe (Ste13p), Drosophi-la melanogaster (ME31B), Xenopus laevis (Xp54), Mus musculus (mmRCK) und Homo sa-piens (hRCK/p54) findet man Proteine, …
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Enhance heme biosynthesis in Saccharomyces cerevisiae
… into the enhancement of heme production in Saccharomyces cerevisiae through Adaptive Laboratory Evolution (ALE) and Atmospheric and Room Temperature Plasma (ARTP) mutagenesis, complemented by strategic nutrient supplementation. Despite the theoretical promise of ALE and ARTP to induce …
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Compaction of chromatin in Saccharomyces cerevisiae
This study investigated the link between the association of the yeast linker histone homologue, Hholp, and the compaction of the yeast genome during stationary phase. The relative gene content of condensed chromatin, fractionated and isolated by sucrose gradient ultracentrifugation from stationary …
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Characterization of Saccharomyces cerevisiae pseudohyphal development
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1994.
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Mitochondrial structure and distribution in Saccharomyces cerevisiae
Mitochondria play diverse roles in the physiology and metabolism of eukaryotic cells. Like most membrane bounded organelles, they cannot be synthesized de novo but grow and split into distinct organelles and must be inherited to daughter cells upon cell division. The structure of the highly dynamic …
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Antikörper gegen Saccharomyces cerevisiae bei Morbus Crohn
Antikörper gegen Saccharomyces cerevisiae bei Morbus Crohn - eine Familienstudie Einleitung: Antikörper gegen Saccharomyces cerevisiae (ASCA) stellen einen spezifischen und sensitiven Marker für Morbus Crohn (MC) dar. Die Ursache für die krankheitsspezifische Prävalenz dieser Antikörper ist …
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The Regulation of NAP4 in Saccharomyces cerevisiae
… activator conserved in eukaryotes. The CBF in Saccharomyces cerevisiae is a multimeric heteromer termed the Hap2/3/4/5 complex. Hap4, which contains the activation domain of the complex, is also the regulatory subunit and is known to be transcriptionally controlled by carbon sources. However, …
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Developing synthetic, minimal promoters in Saccharomyces cerevisiae
… length of promoters in the popular host strain Saccharomyces cerevisiae was minimized. The core region is first addressed by establishing promoter libraries with minimized de novo cores. Synthetic cores are isolated from a short promoter library and are evaluated in six DNA contexts to establish …
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Exploring Polyphosphate Biology Regulation in Saccharomyces cerevisiae
À la demande de l'auteur, le résumé a été retiré en raison de la nature confidentielle de la thèse. Il sera ajouté une fois la période d'embargo terminée. At the author’s request, the abstract has been removed due to the confidential nature of the thesis. It will be added once the embargo period …
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Expressionsregulation der Sac1 Lipidphosphatase in Saccharomyces cerevisiae
Phosphoinositide sind wichtige Lipidsignalmoleküle, die an der Regulation vieler intrazellulärer Vorgänge beteiligt sind. Sie werden durch das Zusammenspiel von spezifischen Lipidkinasen und Lipidphosphatasen reguliert, die selbst einer genauen Regulation unterliegen müssen. Die Lipidphosphatase …
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Regulation of Morphogenetic Events in Saccharomyces cerevisiae
… best understood for the model budding yeast, Saccharomyces cerevisiae. Once the cell is committed to enter the cell cycle by activation of G1 cyclin/cyclin-dependent kinase (CDK) complexes, the polarity regulator Cdc42 becomes concentrated at the presumptive bud site, actin cables are oriented …
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Harnessing Saccharomyces cerevisiae Genetics for Cell Engineering
Cell engineering holds the promise of creating designer microorganisms that can address some of society's most pressing needs, ranging from the production of biofuels and drugs to the detection of disease states or environmental contaminants. Realizing these goals will require the extensive …
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Engineering Saccharomyces cerevisiae for cellulosic ethanol production
… obstacles for cellulosic ethanol production in Saccharomyces cerevisiae. The first one is inefficient xylose utilization and the second one is sequential fermentation of glucose and xylose in engineered Saccharomyces cerevisiae. This study mainly focused on solving these two problems by using …
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Aneuploidy causes proteotoxic stress in Saccharomyces cerevisiae
Gains or losses of entire chromosomes lead to aneuploidy, a condition tolerated poorly in all eukaryotes analyzed to date. How aneuploidy affects organismal and cellular physiology is only beginning to be understood. Aneuploidy also has a profound impact on human health; it is the leading cause of …
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Genetic analysis of longevity in Saccharomyces cerevisiae
… Replicative life span in the budding yeast, Saccharomyces cerevisiae is defined as the number of daughter cells produced by a mother cell prior to senescence. The isolation and characterization of genes and interventions that extend mother cell life span can provide insight into the …
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Regulation of mitotic exit in Saccharomyces cerevisiae
… CDKs must be inactivated. In the budding yeast, Saccharomyces cerevisiae, the Cdcl4 phosphatase promotes mitotic exit by antagonizing mitotic CDKs. The activation of this phosphatase is controlled by the mitotic exit network (MEN), a Ras-like signaling cascade essential for exit from mitosis. The …
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