Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"SYT11"”.
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Effects of Ca2+, microRNAs, and rosuvastatin on insulin-secreting beta cell function
… of the exocytotic proteins STXBP1, SNAP25 and SYT11. In this paper I also made the novel observation that SYT11 increase basal insulin secretion and decrease rapid exocytosis, two phenomenons associated with T2D. The work on miR-335 emphasizes the importance of miRNAs in the regulation of the …
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Exocytosis in Type 2 Diabetes- Functional and genetic studies of hormone secretion
… donors which revealed that STX1A, SYT4, SYT7, SYT11 and SYT13 is nominally down-regulated in T2D beta-cells and concomitantly correlate positively with glucose stimulated insulin secretion (GSIS) and negatively with HbA1c levels. Furthermore, silencing of Syt4, Syt7 and Syt13 in INS1-832/13 …
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Novel Regulators of Cellular Secretion Alter The Tumor Microenvironment to Drive Metastasis
… its interaction with a trafficking protein, Syt11. These changes in the Golgi dynamics alter the extracellular matrix and the immune landscape to promote invasion and metastasis. Inhibiting Impad1 disrupted the cancer cell secretome, reversed the invasive phenotype, and enhanced anti-tumor …