Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 111 for “"SWI"”.
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MR Spectroscopy and SWI: Neuropsyehological Outcome after Pediatric Brain Injury
… (MRS) and Susceptibility Weighted Imaging (SWI) when predicting long-term neurocognitive functioning in pediatric TBI patients. Twenty children/adolescents (mean age 13.3 years, 5.8 SD) treated at Loma Linda University Children's Hospital for a head injury were administered measures of …
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SWI/SNF COMPLEXES COORDINATE WITH HISTONE MODIFICATIONS TO REGULATE CHROMATIN REMODELING
SWI/SNF, the founding member of ATP dependent chromatin remodelers and its paralog RSC in yeast perform similar yet distinct functions inside the cell. In vitro these complexes use ATP dependent DNA translocation to either mobilize or disassemble nucleosomes. However, how these complexes interact …
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Engineering Cell Lines to Investigate the Function of Mammalian SWI/SNF Complexes
Mammalian SWI/SNF complexes belong to the class of chromatin remodelling complexes, and consist of approximately 15 subunits. Bioinformatics analyses of tumour sample sequencing studies have shown that members of the mSWI/SNF complexes are mutated in almost 20% of all cases, suggesting many …
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Genetic interactors of the SWI/SNF chromatin remodelling complex in Caenorhabditis elegans
… processes such as transcription and replication. SWItch/Sucrose Non-Fermenting (SWI/SNF) complexes are a family of chromatin remodellers that are conserved across eukary- otes. Mutations in subunits of SWI/SNF complexes cause a multitude of different developmental disorders including Coffin-Siris …
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The Functional Roles for SWI/SNF Chromatin Remodeling Complexes in Physiology and Disease
… studies have implicated multiple subunits of SWI/SNF complexes in human neurodevelopmental and psychiatric disorders, as well as in cancers. Particularly haploinsufficiency of ARID1B, a SWI/SNF chromatin-remodeling subunit, has been implicated in short stature, autism spectrum disorder, …
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AN INSIGHT INTO DIFFERENT MODES OF REMODELER REGULATION: FOCUS ON SACCHAROMYCES CEREVISIAE SWI/SNF
… we have addressed these questions using the SWI/SNF remodeler from budding yeast (Saccharomyces cerevisiae) to explore how different remodelers compare to SWI/SNF in terms of nucleosome interaction. Using a chemical based histone – remodeler photo-crosslinking and labeling approach, we show …
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THE INTERPLAY OF HISTONE CHAPERONE NAP1 WITH SWI/SNF FAMILY OF CHROMATIN REMODELLERS IN S.cerevisiae
… disassembly. We have previously shown that SWI/SNF has the ability to mediate disassembly of a dinucleosome substrate in a two step process. The first step in this process is the displacement of one H2A-H2B dimer that occurs rapidly, followed by a slower step in which the remaining hexasome …
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STRUCTURAL AND FUNCTIONAL DELINEATION OF SUBUNITS AND DOMAINS IN THE SACCHAROMYCES CEREVISIAE SWI/SNF COMPLEX
… been addressed using the prototype remodeler SWI/SNF from budding yeast. ySWI/SNF is a 12 subunit complex that includes the catalytic subunit Swi2/Snf2. It affects 6% of the yeast genome being primarily involved in gene activation. We employed a systematic protein or domain deletion strategy …
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Investigating the role of SWI/SNF chromatin remodelling complex in Clear Cell Renal Cell Carcinoma
SWI/SNF related ATP-dependent chromatin remodelling complexes act to regulate chromatin accessibility, ensuring that genes are regulated appropriately. Components of the complexes are mutated in approximately 20% of human cancers. PBRM1 is one of defining subunits of the PBAF subtype of SWI/SNF …
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SWI/SNF-NUCLEOSOME INTERACTIONS AND DISASSEMBLY OF NUCLEOSOMES: NOVEL METHODOLOGIES FOR MAPPING PROTEIN-PROTEIN AND PROTEIN-DNA INTERACTION
… Southern Illinois University Carbondale. TITLE: SWI/SNF-NUCLEOSOME INTERACTIONS AND DISASSEMBLY OF NUCLEOSOMES: NOVEL METHODOLOGIES FOR MAPPING PROTEIN-PROTEIN AND PROTEIN-DNA INTERACTION MAJOR PROFESSOR: Dr. Blaine Bartholomew The SWI/SNF complex disrupts and mobilizes chromatin in an …
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LDB-1 AND SWI/SNF CHROMATIN REMODELING COMPLEX PARTICIPATE IN THE TRANSCRIPTIONAL ACTIVATION BY C. ELEGANS BLIMP1/PRDM1
Caenorhabditis elegans BLMP-1 is the ortholog of the human zinc finger and SET domain-containing transcriptional repressor BLIMP1/PRDM1. BLIMP1/PRDM1 and its orthologs are well studied as transcriptional repressors in many species including humans and mice. Interestingly, we found that in C. …
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THE CELL CYCLE GENES REGULATION OF IPS CELLS AND THE ROLE OF SWI/SNF CHROMATIN REMODELING ENZYMES DURING THEM DIFFERENTIATION
Lo stato di cellula pluripotente può essere raggiunto con l'espressione ectopica di alcuni fattori di trascrizione che possono riprogrammare le cellule somatiche. (Takahashi, K., e Yamanaka, S., 2006; Takahashi, K., e Yamanaka, S., 2007).
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Ntsongohato Eka Xitsonga (Dimunitives in Xitsonga)
… naswona wu landzelela xivumbeko xa nkoka, leswi vulaka leswaku wu langutisa eka timhaka ta nkoka leti hlamuseriwaka hi ntsongohato kungari tinomboro. Mahungu ma hlengeletiwile hi ku tirhisa maendlelo ma khopasi, hi ku tsavula mahungu eka matsalwa ya ntlhanu ya tinovhele. Eka tinovhele ku …
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Post cardiac surgery sternal wound sepsis burden, risk factors and outcomes at Red Cross War Memorial Children's Hospital, Cape Town, South Africa: a five-year experience
Purpose Sternal wound infection (SWI) is associated with significant morbidity and mortality in postoperative cardiac patients. We aimed to describe the burden, risk factors and outcomes of SWI in post-operative paediatric cardiac patients at a tertiary children's hospital. Methods We conducted a …
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Mpaluxo wa swivuriso swo vulavula hi vavasati eka Xitsonga
… lowu wu kongomisa eka ku lavisisa ndlela leyi swivuriso swa Xitsonga swi hlamuselaka vavasati ha yona. Ririmi ri khumba swilo swo tala swo fana na switekatekisana, tinsimu, swivulavulelo, mitsheketo, mitshayilo na swivuriso. Ndzavisiso lowu wu xopaxopa swivuriso. Swivuriso hi swin’wana swa …
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The role of the SWI/SNF ATP dependent chromatin remodelling complex in the regulation of the human hair follicle cell proliferation and control of the human cutaneous wound healing
… are involved in gene activation and repression. SWI/SNF ATP-dependent chromatin remodelling complexes contain either BRG1 or BRM as the core ATPase together with other common and variable subunits. BRG1 is required for terminal epidermal differentiation in mice and humans and for hair follicle …
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Nxopaxopo wa maendli mo susa ma xiendliwa xinwe eka Xitsong hi ku kongomisa eka tinxakankulu tinharhu ta: Basisa, Sula na Susa
… tiagumente ta nhlokomhaka na tiagumente ta swiendliwa, xikan’we na ku lavisisa michumu leyi nga tirhaka tanihi switirho swa maendli mo susa. Rhavi ra vumbirhi rona ri langutana na ku lavisisa maendli mo susa ma xiendliwa xin’we lama paluxaka mukhuva na mbuyelo lama tirheke eswivulweni ma ri …
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Nxopaxopo wa swivuriso swa Xitsonga swo vulavula hi swiharhi hi ku kongomisa eka ndlela leyi swi paluxaka hayona mahanyelo ni mavonelo ya vutomi ya Xitsonga
Xikongomelo xa ndzavisiso lowu i ku xopaxopa swivuriso swa Xitsonga leswi tshuriweke ku suka eka swiharhi swa le nhoveni na swiharhi swa le kaya (swifuwo) ku endlela ku kombisa hilaha swi paluxaka mahanyelo ni mavonelo ya vutomi ya Vatsonga eka swiyenge swa vutomi leswi landzelaka: rirhandzu na …
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Imaging Iron Content In Patients With Multiple Sclerosis Using Magnetic Resonance Imaging
… used, known as susceptibility weighted imaging (SWI) compared to other conventional MR techniques and rapid-scanning X-ray fluorescence in MS cadaver brains. Then, we use SWI phase images to assess iron content in the deep gray matter structures of MS patients compared to normal controls. …
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Nkanelo wa matimba na tipolitiki swa mathyelo ya mavito hi ku kongomisa eka tinovhele ta Xitsonga (The analysis of power and politics of naming with special reference to Xitsonga novels)
… nhlamuselo swa swona hi xikongomelo xo thumbha swihlawulekisinene na nkalaswihlawulekisinene swa hilaha mathyelo ya nga xiswona. Mavito ya ni xiave xa nkoka eka xivumbeko xa ririmi ra tsalwa. Ndzavisiso lowu wu xopaxopile mavito hi xikongomelo xo kombisa timhaka ta ndhavuko leti kucetelaka ku …
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