Global ETD Search
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Showing 1 to 2 of 2 for “"SUV420H1"”.
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Role of ORCA and ORC in chromatin organization and DNA replication
… including G9a, GLP, Suv39h1 (H3K9me2/3), Suv420h1/h2 (H4K20me2/3) and EZH2 (H3K27me3). Removal of ORCA from human cells causes aberrations in the chromatin architecture. I therefore propose that ORCA acts as a scaffold protein that enables the formation of multiple histone lysine …
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Neuromuscular Deficits Associated With KMT5B Haploinsufficiency in Mice
Variation in KMT5B is considered a neurodevelopmental disorder risk and correlated to an autism diagnosis in patients. Patient symptoms include hallmark autism phenotypes along with additional symptoms such as seizures and motor deficits. These motor deficits are characterized as hypotonia and …