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Showing 1 to 3 of 3 for “"SU5402"”.

  1. FGF signaling in Xenopus laevis lens regeneration

    … in vitro using a small molecule inhibitor (SU5402) and dominant negative FGFR1. Both experiments demonstrated that lens regeneration is inhibited upon FGFR signaling inhibition, indicating the necessity of FGFR signaling in lens regeneration. Finally, the sufficiency of various factors for …

    uiuc Repository record for FGF signaling in Xenopus laevis lens regeneration (opens in a new tab)

  2. KGF-1 and KGF receptor expression in human periodontal disease and in vitro microwounding-associated-ligand-independent KGFR activation

    … cell migration was reduced by PP1 (82.7%), SU5402(70%) and PD98059 (57%). Conclusions: KGF-1 and KGFR proteins are expressed in health but significantly induced in human diseased periodontal tissues. Microwounding associated generation of ROS mediates KGFR phosphorylation via c-Src kinase …

    ubc Repository record for KGF-1 and KGF receptor expression in human periodontal disease and in vitro microwounding-associated-ligand-independent KGFR activation (opens in a new tab)

  3. Limb cell behaviors in Monodelphis domestica growth and development: the effects of Fgf pathway activators and inhibitors

    A fundamental question in biology is, “how is growth differentially regulated during development to produce organs of particular sizes?” Research in invertebrates has shown that answers to this question can be gained by studying how serially homologous organs of a single animal (e.g., Drosophila …

    uiuc Repository record for Limb cell behaviors in Monodelphis domestica growth and development: the effects of Fgf pathway activators and inhibitors (opens in a new tab)