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Showing 1 to 10 of 10 for “"STR analysis"”.
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Evaluation of storage conditions on DNA used for forensic STR analysis
Short tandem repeat (STR) analysis is currently the most common method for processing biological forensic evidence. STRs are highly polymorphic and allow for a strong statistical power of discrimination when comparing deoxyribonucleic acid (DNA) samples. Since sample testing and court proceedings …
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The Use And Development Of Laser Microdissection To Separate Spermatozoa From Epithelial Cells For Str Analysis
Short Tandem Repeat (STR) analysis has become a valuable tool in identifying the source of biological stains, particularly from the investigation of sexual assault crimes. Difficulties in analysis arise primarily in the interpretation of mixed genotypes when cell separation of the sexual …
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Degenerate Oligonucleotide Primed - Polymerase Chain Reaction Evaluation And Optimization To Improve Downstream Forensic STR Analysis Of Low Quality/Low Quantity DNA
… yield low quality/low quantity DNA, thecurrent STR analysis methods do not generate acceptable profiles. Whole genomeamplification can be used to pre-amplify the entire genome for downstream analyses. A commercially available kit for DOP-PCR, a form of WGA, is currently being used in the …
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A Novel Forensic DNA Profiling Method Based On Molecular Beacons Without Dna Purification
<p>Analysis of polymorphisms in nucleic acid sequences provides the basis for identification of individuals and their genetic deficiencies. Currently, the accepted method of analysis for profiling is Short Tandem Repeat (STR) profiling. This is a lengthy process, typically taking up to 3 days. The …
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Substrate analogs to investigate alkaloid biosynthesis in Catharanthus roseus
… and secologanin, which are coupled to form strictosidine by the enzyme strictosidine synthase (STR). Analysis of the tryptamine substrate specificity of strictosidine synthase (STR) revealed a subset of tryptamine analogs which were converted to the corresponding strictosidine analogs. The …
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Development of Bioinformatic Methods for Data-Driven Forensic Short Tandem Repeat Analyses
Short tandem repeats (STRs) are a class of markers which currently play an important role in the forensic DNA typing. The arrival of massively parallel sequencing platforms (MPS) in forensic science reveals new information such as insights into the complexity and variability of the markers that …
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Performance Efficacy Using A Comparison Of Commerical And In-house Y-str Multiplex Systems For Operational Use
… States have the capability of performing Y-STR analysis in casework. In order to aid in facilitating the transfer of Y-STR technology to the crime laboratory community for operational use, a comparison between commercial products from three main vendors (Applied Biosystems AmpFLSTR Yfiler …
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Evaluation of insertion / deletion polymorphisms (INDELs) applied to forensic casework in Malaysia
… sun and humidity for days or even months. STR analysis is widely accepted by forensic community, but sometimes this technique gives unreliable results when profiling degraded samples as the amplicons size are relatively larger (100 bp to 450 bp). While, miniSTR is a reduced size of STR …
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Investigation of the Effects of Environmental Insults on Presumptive and Confirmatory Tests and DNA Degradation
… and saliva is an integral part of the forensic analysis, which determines the course of downstream genetic analysis. Body-fluid samples are routinely found to be affected by local environmental insults such as UV radiation, high temperatures and humidity, compromising the quality of the samples …