Global ETD Search
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Showing 1 to 3 of 3 for “"STE2"”.
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Structure and activation of the class D GPCR dimer Ste2
… critical for their survival and reproduction. Ste2 (sterile-2 α-factor pheromone receptor) is a prototypical class D GPCR found in the baker’s yeast Saccharomyces cerevisiae and is critical for pheromone-sensing and sexual mating in yeast. Ste2 was the first ligand-binding GPCR to be sequenced, …
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Untersuchung von Proteinkomponenten der ER-Golgi Recycling-Maschinerie von Hefe
… vermittelte ER-Retention wurde mit Hilfe des Ste2-Wbp1p Reporters analysiert, der bei gestörter Rückführung zum ER zur Plasmamembran fehllokalisiert wird. Mit Hilfe von multi-copy"-Plasmiden wurde ein Gen isoliert, dessen Genprodukt bei Überproduktion den Recyclingmechanismus beider Reporter …
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Activation mechanisms of non-class A G protein-coupled receptors
… 1 receptor (PAC1R), and fungal Class D receptor STE2, using large-scale all atom unbiased molecular dynamics simulations. To overcome the limitations associated with traditional MD simulations, we employ multiple adaptive sampling strategies to sample rare events faster. To overcome the sampling …