Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"STD NMR"”.
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Biophysical and structural studies of novel F420-dependent oxidoreductases in Mycobacterium tuberculosis
… (ITC), saturation transfer difference (STD) NMR, and X-ray crystallography. Although recent studies have drawn attention to F420 due to its role in activating the promising anti-tuberculosis drug PA-824, little is known about the function of this coenzyme in Mtb metabolism. In order to …
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Exploration of Small Peptide Binding Interactions with Inorganic Surfaces Across Timescales
… through mutation studies, solid state NMR, DEST, NOSEY, and STD-NMR experiments. Likewise, the α-1 fragment of osteocalcin was investigated via binding isotherms for its ability to bind to both hydroxyapatite and titania, and its method of binding to the later was studied through solid …
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Discovery of novel antibacterial and antitubercular compounds using chemical genetics and computational approach targeted at phospholipid biosynthesis
… difference - nuclear magnetic resonance (STD-NMR) spectroscopy of these proteins should also be considered in the event of further futile attempts.
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Discovery of novel highly selective Rho kinase (ROCK) inhibitory peptides and evaluation of their biological activities
… binding. This binding was furtherly confirmed by STD-NMR. Furthermore, the high selectivity of Peptide25 was evaluated on a panel of 182 protein kinases selected from various protein kinase families. Finally, the activities of newly developed ROCK1 inhibitory peptide and its derivatives were …
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Cytoplasmic sensing by Bacillus subtilis chemoreceptors
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-11 without embargo terms
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CHARACTERIZATION OF THE INTERACTION BETWEEN HEPARAN SULFATE AND THE SPIKE (S) PROTEIN OF THE LATEST SARS-COV-2 VARIANTS
… and experimental approaches that combine NMR spectroscopy and different computational tools. We have selected two hexasaccharides as HS mimetics to probe their interactions with different RBDs using docking calculations. We then focused our study on the Omicron variant and one of the …