Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"SS18-SSX"”.
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DEFINING THE ROLE OF THE PCGF3-CONTAINING POLYCOMB REPRESSIVE COMPLEX 1 IN SYNOVIAL SARCOMA
… and therapeutic options. The fusion protein SS18-SSX, found in over 95% of cases, is considered the primary oncogenic driver, disrupting BAF complexes and redirecting them to Polycomb repressive domains, thus activating them. This mislocalization depends on the higher affinity of the fusion …
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Genetic Profiling in Soft Tissue Sarcoma
… established expression patterns related to the SS18-SSX fusion variants and metastatic potential in synovial sarcoma (SS). The differential expression of various developmental genes, transcription factors, histones, and metallothioneins suggests that the gene fusion variants have distinct …