Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 47 for “"SRH"”.
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Development of an Improved Synthesis of S-D-Ribosyl-L-Homocysteine (SRH) and Progress Toward SRH Analogs Modified at the C3 Position
… by the enzyme LuxS from the precursor SRH. This thesis describes an improved synthesis of SRH through the exploration of different protecting group strategies. The knowledge gained from the improved synthesis of SRH is then applied toward the synthesis of SRH analogues with increased …
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Biochemical Evaluation of SRH Analogs as Potential LuxS Inhibitors
… of AI-2 from <em>S</em>-ribosyl homocysteine (SRH) in a wide variety of bacterial species. Inhibition of LuxS would therefore inhibit interspecies quorum sensing. The goal of this project is to establish biochemical assays for the evaluation of small molecules as potential LuxS inhibitors. The …
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Female sex workers'experiences of the sexual reproductive health(SRH)services on the emerging voices project in Chipata district in Zambia
… them from accessing Sexual Reproductive Health (SRH) services thereby increasing the risk of infections and re-infections of HIV/AIDS and Sexually Transmitted Infections(STI’s) among them and their partners who may be the general population. The Southern African AIDS Trust (SAT Zambia) identified …
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Female sex workers'experiences of the sexual reproductive health(SRH)services on the emerging voices project in Chipata district in Zambia
… them from accessing Sexual Reproductive Health (SRH) services thereby increasing the risk of infections and re-infections of HIV/AIDS and Sexually Transmitted Infections(STI’s) among them and their partners who may be the general population. The Southern African AIDS Trust (SAT Zambia) identified …
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Synthesis of S-Ribosyl-L-homocysteine and Analogs Modified at the Homocysteine-C3 Position
… converts <em>S</em>-ribosyl-L-homocysteine (SRH) into homocysteine (HCys) and 4(<em>S</em>),5-dihydroxypentane-2,3-dione (DPD), which is the precursor of autoinducer-2 (AI-2). Thus, inhibitors of LuxS could prevent QS by halting the conversion of SRH to AI-2 rendering the cell …
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Investigations of Thioether Generation for S-D-Ribosyl-L-homocysteine Synthesis
… molecule <em>S</em>-D-ribosyl-L-homocysteine (SRH). Although previous preparations of SRH and its analogues have been reported in the literature, they employ assorted methods with varied results. Therefore, a reassessment of the methodology used for synthetic preparation of the thioether bond …
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Communication guidelines to support grandparent headed families regarding sexual and reproductive health in Tshwane District
… The four themes are PHCNs' experiences of SRH communication, PHCNs' experiences of factors facilitating SRH communication, PHCNs' experiences of SRH communication barriers and PHCNs' recommendations for SRH communication promotion. Four (4) essences and ten (10) constituents emerged from …
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An exploratory descriptive study of the sexual and reproductive health knowledge of postgraduate students at the University of Cape Town.
… knowledge of sexual and reproductive health (SRH) is low. This study was conducted in response to the dearth of information about the sexual and reproductive health knowledge of postgraduate students. Research conducted to explore the SRH knowledge of undergraduate students suggests that the …
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Utilisation of sexual and reproductive health services from adolescent friendly health services in Nepal
… addressing the sexual and reproductive health (SRH) of adolescents. Since 2009 Nepal has been integrating AFHS into its public health facilities. Despite much attention, and attempts to scale up AFHS, utilisation remains suboptimal. This thesis, therefore, aims to understand the factors …
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Food access, self-rated health, and diabetes self-efficacy among prenatal women in the context of the COVID-19 pandemic
… perception of their health [self-rated health (SRH)], ultimately impacting their health and overall wellbeing. Individuals with poor access to food have a two-fold higher risk of developing diabetes compared to those with secure food access. The first research question, therefore, identified …
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Perceptions on the use of sexual reproductive health services by female school going adolescents: a case of Lusaka East.
… the use of Sexual Reproductive Health Services (SRH) services by female school-going adolescents in four secondary schools in the Eastern part of Lusaka. The study applied a qualitative research approach and a case study was used. The female school-going adolescents were purposively selected to …
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Health Provision in Tshitshi, Zimbabwe: A Focus on Sexual and Reproductive Health
… in particular sexual and reproductive health (SRH) services, are accessed by the most severely disadvantaged segment of the population: people living in rural areas. This study explores how the economic crisis shapes Tshitshi women's access to and use of SRH services. Specifically, it maps out …
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Biochemical Assay Optimization and Computational Screening Efforts to Identify Potential LuxS Inhibitors
… from <em>S-</em>ribosylhomocysteine (SRH) by the enzyme LuxS and induces interspecies cell-to-cell communication. Inhibition of LuxS would therefore inhibit interspecies QS. Herein, a search for novel molecular species that will competitively bind with SRH in the LuxS binding site is …
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Early Adversity and Cardiovascular Stress Response: Stress Reactivity Or Biological Sensitivity to Context
The stress reactivity hypothesis (SRH) posits highly stressful early environments contribute to exaggerated cardiovascular (CV) reactivity and/or slower CV recovery, which in turn contributes to CV disease. These associations are well-supported in the literature; however, a growing number of …
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Community perceptions and factors associated with contraceptive use among adolescent females in Mazabuka district, Zambia
… Adolescent sexual and reproductive health (SRH) has increasingly been on national health agendas of many countries, including Zambia. One of the major causes of these agendas is the concern against early childbearing. Access to youth-friendly health services such as contraceptives is vital …
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Surface and bulk passivation of multicrystalline silicon solar cells by silicon nitride (H) layer : modeling and experiments
… velocity can be described by Shockley-Read-Hall (SRH) statistics. Current SRH formalisms have failed to explain the surface recombination mechanism in terms of injection level dependence as has been observed by lifetime measurements. Previous SRH modeling result shows that very high Qf (up to …
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Impacts of cold pool strength on tornado production in quasi-linear convective systems
… vertical wind shear and storm-relative helicity (SRH) were obtained from hourly 13 km resolution Rapid Refresh model (RAP) analyses at the nearest hour prior to the arrival of the QLCS cold pool. Every ASOS site selected to represent a QLCS was classified as featuring a tornadic environment or a …
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Social Capital and Self-rated Health: testing association with longitudinal and multilevel methodologies
… social capital proxies and self-rated health (SRH), alongside other well-known health determinants, using multilevel and longitudinal data, whilst employing a variety of study designs and methods. All data used in this thesis come from the United Kingdom’s British Household Panel Survey (BHPS) …
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An exploration of the determinants of sexual risk behaviour among adolescent girls and young women aged 15-24 years in South Africa: a sub-study of the 2019-2022 HERStory2 study
… lead to adverse sexual and reproductive health (SRH) outcomes, including HIV, STIs, unplanned pregnancies, and forced sex. By exploring the perspectives of AGYW and community stakeholders, the study seeks to enhance future interventions aimed at reducing the risk of STIs, including HIV, and …
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Factors that influence adolescents condom use decision-making in the Western Cape, South Africa
… in aligning sexual and reproductive health (SRH) interventions and supporting healthy SRH decision-making and healthy relationships for adolescents.
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