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Showing 1 to 2 of 2 for “"SPR-5"”.

  1. The Polycomb Complex 2 contributes to developmental delay when histone methylation is inappropriately inherited

    … H3K4me is removed by the H3K4 demethylase, SPR-5, and H3K9me is subsequently added by the histone methyltransferase, MET-2. Recently, it was demonstrated that SPR- 5 and MET-2 maternal reprogramming antagonizes the H3K36 methyltransferase, MES-4, which maintains a transcriptional memory of a …

    kennesaw Repository record for The Polycomb Complex 2 contributes to developmental delay when histone methylation is inappropriately inherited (opens in a new tab)

  2. Analysis and suppression of mutant sel-12 in Caenorhabditis elegans

    … the sel-12 Egl defect. In several screens four spr genes (suppressor of presenilin) were identified, which are able to suppress both sel-12 defects in the egg-laying system. The spr genes are not able to influence LIN-12/Notch signaling directly but require the activity of the second C. elegans …

    lmu-germany Repository record for Analysis and suppression of mutant sel-12 in Caenorhabditis elegans (opens in a new tab)