Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"SPI-1"”.
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Studies on the control and activity of the Salmonella spi-1 regulator HilD
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-04-06 without embargo terms
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Natural product discovery in actinomycetes and investigation into the regulation of SPI-1 in salmonella typhimurium
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-08-01
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Salmonella Typhimurium infections in pigs: a closer look at the pathogenesis
… zijn op het Salmonella Pathogeniciteitseiland 1 (SPI-1). Deze genen waren essentieel voor Salmonella Typhimurium om varkensdarmcellen en macrofagen te kunnen binnen dringen. Alle SPI-1 mutanten waren sterk verzwakt in hun vermogen om diarree te veroorzaken. Zowel vroege als late celdood werd …
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Genetic and environmental regulation of virulence genes in Salmonella enterica serovar Typhimurium.
… on the Salmonella pathogenicity island 1 (SPI-1). This work demonstrates that CsrA in S. typhimurium like its counterpart in E. coli regulates expression of genes required for flagellar synthesis and suggests a role for CsrA in the positive regulation of utilization of propanediol and …
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Structural and Functional Characterization of SPOA Domains in Salmonella Typhimurium Type III Secretion Systems
… interactions in the Salmonella typhimurium SPI-1 sorting platform protein SpaO (Chapter 2). In Chapter 3, I structurally characterize the interaction of the heterotypic SPOA complex with a regulator of the SPI-1 ATPase and demonstrate the necessity of the interaction for T3SS secretory …
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Understanding small RNA-mediated post-transcriptional regulation of Salmonella pathogenicity island 1 activator HilA in Salmonella typhimurium
Salmonella Pathogenicity Island 1 (SPI1) encodes a Type-3 secretion system (T3SS) essential for Salmonella invasion of intestinal epithelial cells. Many environmental and regulatory signals control SPI1 gene expression, but in most cases, the molecular mechanisms remain unclear. Many regulatory …
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Role of Salmonella enterica subspecies enterica serovar Enteritidis pathogenicity island-2 in chickens
… Salmonella pathogenicity islands 1 and 2 (SPI-1 and SPI-2) each encode a specialized type III secretion system (T3SS) that enables Salmonella to manipulate host cells at various stages of the invasion/infection process. The SPI-2 T3SS has been identified as vital for survival and …
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An analysis of selected secretion systems of Pseudomonas species
… discovered that P. fluorescens F113 uses the SPI-1 T3SS to avoid amoeboid grazing in mixed populations. This finding may represent a significant aspect of F113 rhizocompetence, and the rhizocompetence of other Rhizobacteria.
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Near Real-time Seasonal Drought Forecasting and Retrospective Drought Analysis using Simulated Multi- layer Soil Moisture from Hydrological Models at Sub- Watershed Scales
… including soil moisture (SM), actual evapotranspiration (ET), potential evapotranspiration ET (PET), and runoff (SURQ) for near-real time drought severity assessment, and drought forecasting for a lead of 9-months. A combination of the surface and total rooting depth soil moisture percentiles …
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Transcriptional regulation in Salmonella enterica by the Lysr-type factor LeuO
… como es el caso de la isla de patogenicidad 1 (SPI-1). La isla de patogenicidad 1 de Salmonella contiene los genes necesarios para invadir el epitelio intestinal. Esta región está sometida a una estricta regulación transcripcional y posttranscripcional. Debido a la presencia de genes de SPI-1 …
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Regulation of Salmonella pathogenicity island I through the hilD mRNA 3' untranslated region
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-05-01
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Further characterisation of the envelope stress responses of Salmonella Typhimurium
… S. Typhimurium virulence through regulation of SPI-1, and as a regulator of post-transcriptional modification through the positive and negative regulation of small regulatory RNAs (invR, omrA and omrB). Our data confirm Cpx contribution to copper tolerance, a positive regulator of the heat shock …
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Mode of Entry and Survival of Salmonella Enterica Serovar Typhimurium in Trophoblast Cells
… in the Salmonella pathogenicity island (SPI)-1 type III secretion system (TTSS) (S.Tm-ΔinvA) were unable to enter epithelial cells, but efficiently infected placental choriocarcinoma cell lines through scavenger receptor-mediated endocytosis. Next, we observed that S.Tm failed to grow …
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Mucin and mucin glycans alter behaviorof mucosal pathogens
… including Salmonella pathogenicity island 1 (SPI-1), which is required for host cell invasion. Together, my results elucidate new ways in which mucin modulates pathogen behavior and opens the possibility to future mucin-based therapeutics.
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Análisis genético y molecular del operon std de salmonella enterica
… conocida como isla de patogenicidad 1 (SPI-1). Otro locus que Salmonella ha adquirido por transferencia horizontal es el operón std, implicado en la formación de fimbrias que participan en la colonización del intestino del hospedador. La expresión del operón std se encuentra reprimida en …
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Investigating Feeding Omega-3 Polyunsaturated Fatty Acids and/or Soy Protein Isolate to Female pck Rats on Polycystic Kidney Disease and Related Complications
… + CO), casein + soybean oil (Casein + SO), SPI + soybean oil (SPI + SO) or SPI + 1:1 soybean/salmon oil (SPI + SB) for 12-weeks. Histological evaluation showed that all rats had renal and hepatic cysts regardless of the dietary group. Rats fed SPI+ SB diet had the highest (P = 0.03) renal …
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Molecular basis of NAIP/NLRC4 inflammasome activation by flagellin
… enterica flagellar filament protein (FliC), the SPI-1 type III secretion system needle (PrgI) and inner rod proteins (PrgJ). Recognition of these bacterial ligands by the NAIP receptors allows oligomerisation with NLRC4 and subsequent recruitment of caspase-1. Caspase-1 mediates pyroptosis, while …
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Resistencia a beta-lactámicos y fluoroquinolonas en Salmonella enterica. Mecanismos moleculares y elementos de movilización génica
… (AMPR) S. enterica isolates obtained from hospitals of five regional communities (including both previously mentioned). Susceptibility to amoxicillin-clavulanic acid (AMCS) was detected in 79 of these isolates, and reduced susceptibility or resistance (AMCI/R) in 124 additional isolates. The …