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Showing 1 to 3 of 3 for “"SOX proteins"”.

  1. Evolutionary patterns of group B Sox binding and function in Drosophila

    … have revealed widespread roles for Dichaete and SoxNeuro, two group B Sox proteins, during fly development. Although they have distinct target genes, these two transcription factors bind in very similar patterns across the genome and can partially compensate for each other's loss, both …

    cambridge Repository record for Evolutionary patterns of group B Sox binding and function in Drosophila (opens in a new tab)

  2. Studying lung development in vitro: expanding the genetic toolbox and analysis of SOX2 and SOX9 function

    … the function of two SRY-related HMG-box (SOX) genes, SOX2 and SOX9, in human foetal lung progenitor cells. I show that although SOX2 is expressed in early stage progenitor cells it is dispensable for progenitor cell survival and self- renewal. By contrast, SOX9 is crucial for tip …

    cambridge Repository record for Studying lung development in vitro: expanding the genetic toolbox and analysis of SOX2 and SOX9 function (opens in a new tab)

  3. The role of Dichaete in transcriptional regulation during Drosophila embryonic development

    Sox domain genes encode a family of developmentally important transcription factors conserved throughout the Metazoa. The subgroup B, which includes the mammalian Sox1, 2 and 3 proteins and their Drosophila counterparts Dichaete and SoxNeuro, are particularly important for the development of the …

    cambridge Repository record for The role of Dichaete in transcriptional regulation during Drosophila embryonic development (opens in a new tab)