Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"SOCS3 (Suppressor Of Cytokine Signaling 3)"”.
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Die Rolle der Janus-Kinasen-spezifischen Insertion (JSI) in JAK2
The Janus Kinase JAK2 is activated by IL-6-type-cytokines. Furthermore it plays an important role within the signal transduction of other cytokines, as for example erythropoetin and growth factors. In the Institute for Biochemistry of the RWTH Aachen, a structured model of the Kinase domain of JAK …
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Prostanoid-mediated Inhibition of IL-6 Trans-Signalling in Pulmonary Arterial Hypertension: a Role for Suppressor of Cytokine Signalling 3?
… disease with no cure. Current treatment consists of a cocktail of vasodilators which relieve symptoms of PAH but do not treat the cause. Thus, there is a need for novel drugs that target the underlying pathological causes of PAH. PAH is a multi-factorial, but one key contributor is the …