Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"SNX9"”.
-
Molecular mechanisms of Sorting nexin-9 in membrane triggered actin polymerisation
Sorting nexin-9 (SNX9) is a SH3-PX-BAR domain-containing adaptor protein, func- tionally implicated in regulating actin polymerisation in clathrin mediated endocy- tosis and filopodia formation. Alterations in SNX9 expression correlate with several stages of breast cancer metastasis, and poor …
-
ENDOCYTIC CONTROL OF CELL-AUTONOMOUS AND NON-CELL-AUTONOMOUS FUNCTIONS OF P53
… the endocytic adaptor protein Sorting Nexin 9 (SNX9) was found to be the most abundant specific interactor of NUMB-1 and NUMB-2. We validated this interaction through in vitro binding, GST-pulldown and co-immunoprecipitation assays, which revealed that NUMB-1/2 and SNX9 participate in tripartite …
-
Modulation of host phosphatidylinositol phosphates by salmonella effector protein SOPB
… PtdIns(3,4)P<sub>2</sub> which recruits host SNX9, a protein involved in actin modulation to the plasma membrane. The 4-phosphatase activity of SopB is solely responsible for the hydrolysis of host PtdIns(3,4)P<sub>2</sub> into PtdIns(3)P which accumulates around the ruffles and becomes …
-
Spatio-temporal properties of membrane-localized actin nucleating complexes
… remodeling. Endocytic accessory proteins such as SNX9 and Dynamin2 were also found to localize to FLS tips. This work provides new insights into the dynamics and organization of protein ensembles at actin nucleation sites, and proposes a novel link between endocytosis and filopodia formation, …