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Showing 1 to 1 of 1 for “"SNP309"”.

  1. Contrasting Effects of An Mdm2 Functional Polymorphism On Tumor Phenotypes

    Ortiz, Guadalupe J, IV, <p>0000-0002-8728-5090</p>2017

    … polymorphisms with cancer risk. The <em>MDM2 SNP309G</em> allele is a cancer-associated functional polymorphism positioned in the <em>MDM2</em> P2 promoter that enhances transcription factor SP1 binding, resulting in elevated levels of MDM2 concomitant with decreased p53 tumor-suppressor …

    uthsc Repository record