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Showing 1 to 2 of 2 for “"SND1"”.

  1. A Study of The Snd1/Prmt5 Axis In Liver Cancer By Genetic Mouse Models

    … nuclease Tudor domain containing 1 (SND1) is an effector that specifically binds SDMA via its single C-terminal Tudor domain. Both SND1 and PRMT5 have been implicated in hepatocellular carcinoma (HCC). SND1 has been confirmed as a driver of HCC using genetically engineered mouse …

    uthsc Repository record for A Study of The Snd1/Prmt5 Axis In Liver Cancer By Genetic Mouse Models (opens in a new tab)

  2. Exploring the role of the arginine-methylation writer-reader pair PRMT5/SND1 in JAK2-mutant myeloproliferative neoplasms

    … Nuclease Domain-Containing Protein 1 (SND1) is the effector molecule responsible for reading the symmetric dimethyl-arginine (SDMA) marks deposited by PRMT5, underpinning a potential critical role in MPN pathogenesis and treatment. SND1 is the only human protein known to contain the …

    uthsc Repository record for Exploring the role of the arginine-methylation writer-reader pair PRMT5/SND1 in JAK2-mutant myeloproliferative neoplasms (opens in a new tab)