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Showing 1 to 3 of 3 for “"SN50"”.
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U0126, MEK1/2 inhibitor, Induces Adhesion Molecules Expression in Human Blood Cells
… rottlerin (an inhibitor for PKC-δ), and SN50 (an inhibitor for NF-kB) on U0126-induced adhesion molecule expression. Adhesion molecule expression was attenuated by rottlerin and trolox. In addition, to examine cell type specificity of U0126 effect on adhesion molecule, we investigated …
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Cellular signalling pathways involved in muscle atrophy in cancer cachexia
… calphostin C (100µM) and NF-kB the inhibitors SN50 (18µM), curcumin (50µM) and resveratrol (30µM), 2 hours prior to the addition of PIF. In vivo studies found the IKK inhibitor resveratrol (1mg/kg) to be successful in attenuating protein degradation (p<0.001) and upregulation of …
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Studies of TNF- α-induced -GSIS Inhibition in INS-1 β-cell
… GSIS inhibition. Decreased GSIS was recoverd by SN50, NFkB inhibitor. TNF-α-induced NFkB activation is thought to be reponsible for TNF-α-induced GSIS inhibition. CONCLUSION: Glucose and insulinotropic stimuli-aminoacid, sulfonylurea, imidazolin-induced insulin secretion was significantly …