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Showing 1 to 14 of 14 for “"SKP"”.
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Application of scanning micro-tip and UHV Kelvin probes in surface and material characterisation.
… work utilising the scanning Kelvin probe (SKP) for surface potential mapping and monitoring changes in work function due to environmental influences in ambient and UHV conditions. The SKP is a truly non-contact technique which determines local work function changes and surface states on …
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Development and application of the scanning Kelvin probe for solar cell defect analysis.
… novel applications of the scanning Kelvin probe (SKP) technique. Initially the capacitive interaction between the Kelvin probe and the sample under analysis was investigated. The limitations of the Kelvin probe as a technique are discussed; specifically the effect stray flux emanating from the …
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Study of semiconductor and metal surfaces using a novel scanning Kelvin probe.
… construction of a novel Scanning Kelvin probe (SKP) compatible with the Ultra-High-Vacuum (UHV) environment - the first automatic, high resolution, UHV-SKP in the UK. The Kelvin Probe is a capacitor device used to measure the work function phi between a vibrating reference electrode (the tip) …
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The Gsk-3Β-Fbxl21 Axis Regulates Tcap Via Ubiquitin-Mediated Proteasomal Pathway In The Cytoplasm
… interacts with both FBXL21 and TCAP and affects Skp, Cullin1(Cul1), F-box containing (SCF) complex/E3 ligase-Substrate complex formation. Interestingly, GSK-3β knockdown significantly inhibited FBXL21-CUL11 and FBXL21-TCAP complex formation. These results revealed a new circadian regulatory …
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Untersuchungen zum zeitlichen Verlauf der Antikörperavidität bei HIV-1-infizierten Patienten mit antiretroviraler Therapie
… n=13); 4. Patienten in der Serokonversionsphase (SKP; n=3). Die Aviditätsbestimmung erfolgte mit Hilfe eines Festphasen-Enzymimmunoassays und 4 M Harnstoff als Elutionsreagenz. Ergebnisse : Unabhängig vom klinischen Status zeigten alle Patienten hohe (>60%) Aviditätswerte für Anti-gp41-IgG. …
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Understanding the protein complexes involved in the reception of the plant hormone Strigolactone
… the downstream signalling proteins, such as the Skp-Cullin-F-box (SCF) E3 ligase complex and target protein(s) to relay the signal. It is known that the receptor undergoes a significant conformational change in the presence of SL and SCF components. At present, it is unclear how the hydrolytic …
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Precise Temporal Regulation of Ribonucleoprotein Complexes during the Drosophila Maternal-to-Zygotic Transition
… and ME31B for degradation early in the MZT; the Skp/Cullin/F-box-containing (SCF) complex targets SMG at the end of the MZT. Deleting the C-terminal 233 amino acids of SMG abrogates interactions with F-box proteins and results in failure of the protein to degrade during the MZT. I map the …
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Fingermark Enhancement on Metallic Surfaces
… and fingermark residues provided by SEM-EPMA and SKP allows for this to be exploited to visualise latent fingermarks on metals. <br/><br/>The ability to create laser ablated nanoparticles in aqueous solutions has allowed their use in latent fingermark enhancement to be investigated for the first …
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ELUCIDATION OF REGULATORY MECHANISMS OF TRANSCRIPTION AND COUPLED mRNA EXPORT
… (Mdm30) component of RING domain-containing SCF (Skp-Cullin-F-box) family of E3 ligases in mRNA export, thereby implicating the role of ubiquitylation in export via non-HECT E3 ligase for the first time. My results show that Mdm30 ubiquitylates Sub2, an integral component of the TREX …
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Regulation of BubR1 by Ultraviolet Radiation: Implications in Skin Cancer
… the substrate recognition subunit for the SCF (Skp, Cullin, F-box) complex, belonging to the Cullin RING E3 ubiquitin ligase (CRL) family of E3 ubiquitin ligases that regulates the stability of a wide range of cellular proteins by recognizing and binding specific substrates through a conserved …
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Untersuchungen zum Integrations- und Translokationsmodus des Sec-Translokons in Escherichia coli
… Interaktion mit dem periplasmatischen Chaperon Skp. Diese Interaktion konnte durch chemische Quervernetzung nachgewiesen werden. Da SecA auch fuer die Translokation periplasmatischer Momp2-Domaenen von weniger als 25 Aminosaeuren benoetigt wurde, scheint SecA eine generelle Rolle bei der …
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New insights into the differential rotation of the inner core
… doublets. We used non-IC reference phase (mainly SKP), which eliminated ambiguity where the temporal changes come from. We found that the temporal changes have always started at refracted PKIKP and the travel time changes correlate better with PKIKP, rather than the PKiKP. Changes in reflected …
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Targeting the N-myc oncoprotein using nanobody technology
… proteins bind, such as the E3 ubiquitin ligase Skp2. Nanobodies against the transactivation domain were more specific for N-myc and were shown to inhibit its Skp-2-mediated ubiquitylation. This could provide novel means of eradicating tumours based on a study showing that inhibition of …
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Vasemmistososialismi 1920-luvun Kuopiossa : Suomen Moskovan uho, nousu ja tuho
… kuitenkin vaikeuksia asemoida joukkoliikkeensä SKP:n, sosialidemokraattien ja oikeiston merkitsemällä poliittisella kentällä. Mihin vasemmistososialistit kuuluivat Suomessa? Eduskuntavaaleissa vasemmistososialististen puolueiden kannatus oli koko tarkastelujakson ajan kolmenkymmenen prosentin …