Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"SK-Mel-28"”.
-
Efeito da sinvastatina na modulação da expressão de Reck e suas isoformas em células de melanoma humano
Resumo: O melanoma e um tipo de tumor que se origina dos melanocitos, sendo altamente resistente as terapias convencionais, especialmente quando se encontra em condicoes de metastase, o que torna necessario a busca por novas alternativas de tratamento. O processo de metastase, em geral, e …
-
Aktivität endogener Retroviren in Tumorgeweben von Primaten
… sind einige der HERV-K Proviren replikationskompetent und besitzen komplette offene Leserahmen für retrovirale strukturelle und enzymatische Proteine. Sie werden häufig in Verbindung mit dem Auftreten verschiedener Tumor- und Autoimmunerkrankungen gebracht. Zudem scheinen einzelne HERV-K …
-
Synergistically active curcumin resveratrol solid lipid nanoparticles for treatment of melanoma
… shown significant potential in the treatment of melanoma due to their multifarious roles in its pathogenesis. Furthermore, the combination of curcumin and resveratrol was found to demonstrate synergistic effects in other cancers; colorectal, breast cancer. However, the highly hydrophobic …
-
Synthesis and biological evaluation of auristatin-F recombinant antibody-drug conjugates for cancer therapy
… assays were undertaken by treating A431, SK-Mel-28, MDA-MB468, Hs578T and A2058 cell lines with ADCs generated from various scFv-SNAP fusion proteins, in which selectivity towards target receptor positive cell lines was demonstrated. Quantification of the efficacy of generated ADCs was …
-
Investigation into the potential of methylene blue and its derivatives to be used in the photodynamic therapy of non-pigmented and pigmented cells
… kidney and spleen. Its long persistence in the skin commonly causes severe photosensitization reactions in patients for up to three months post-treatment. Photofrin® also has poor light absorption properties within the therapeutic window (600 to 800 nm) for PDT. Furthermore, PDT with Photofrin® …