Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 194 for “"SK"”.
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SK Channel Modulators as Drug Candidates and Pharmacological Tools
… and intermediate-conductance Ca2+ activated K + (SK/IK) channels play a fundamental role in the regulation of neurons in the central nervous system. In animal models, SK/IK channel positive modulators have been shown to be effective in reducing the symptoms of neurological diseases such as ataxia. …
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Dopravní řešení okolí ulice Generála Klapku v Komárně (SK)
… řešení ulice Generála Klapku v Komárně, na Slovensku. Celkem byly zpracovány 3 varianty řešení. Všechny varianty byly vypracovány ve formě studie, do výkresů situací, vzorových řezů. Součástí práce je také dopravní průzkum a průzkum lokality. Cílem této práce je zlepšit dopravní situaci v dané …
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The capacity of Montreal Lake, SK to provide safe drinking water
… improvement and continues to pose health risks. As a result, there is a growing interest in the ability of First Nations communities to effectively manage their drinking water resources. The purpose of this study was to assess the capacity of Montreal Lake, SK to provide its residents with …
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NEU4L INDUCES ALTERATIONS ON CELL PROLIFERATION AND DIFFERENTIATION IN NEUROBLASTOMA CELL LINE, SK-N-BE
… Neu4L in human neuroblastoma cells, SK-N-BE. The first important consequence was a marked acceleration of proliferation rate assessed by increase of 3[H]thymidine incorporation (+ 36%), by cell count for up to 4 days (+36%), by MTT test for up 4 days (+26) and by soft agar assay. …
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An X-ray spectroscopic study of the SMC X-1/Sk X-ray binary system
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Physics, 1999.
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Experiences of professionals working with pre-adolescent children who are using psychoactive substances in Regina, SK
… with children and their families in Regina, SK. Five key themes emerged from the study: (1) the main pathway that leads to pre-adolescents receiving addictions services is through family involvement with child protection services; (2) a system of services within Regina, SK is fractured with …
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Purification and Characterization of the Plasminogen Activator From the Human Neuroblastoma Cell Line, Sk-N-Sh
… produced by the human neuroblastoma cell line, SK-N-SH, has been purified and its enzymatic, immunological, and physical properties have been characterized and compared to the properties of human urokinase. The purification scheme involves concentration of the SK-N-SH
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Effekte der Stimmungsstabilisatoren Lithium, Valproat und Lamotrigin auf die Cyclooxygenase-2-Synthese in SK-N-SH Neuroblastomzellen
… induzierte Cyclooxygenase-2-Synthese in humanen SK-N-SH Neuroblastomzellen mittels Western Blot und Enzymimmunoassay untersucht werden. <br>VPA erwies sich als potenter Hemmer der Interleukin-1beta induzierten COX-2-Synthese. Unter chronischer Inkubation mit VPA stellte sich die COX-2-Synthese, …
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ADENOSINE SYSTEM DYNAMICS AND SK CHANNELS MODULATE BASOLATERAL AMYGDALA PYRAMIDAL CELL EXCITABILITY: IMPLICATIONS FOR ANXIETY DISORDERS AND COMORBID ETHANOL ABUSE
Alcohol use disorders (AUDs) impart serious social and economic costs on society. For example, nearly 1 in 18 Americans abuses or is addicted to alcohol, contributing nearly $234 billion per year in socioeconomic costs. Despite this, effective pharmacological treatments remain elusive. To aid in …
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Detection of SK2 Channels on Hippocampal Neurons
… small conductance potassium channels (SK) are crucial for synaptic plasticity, sleep, and learning and memory (Hammond, Bond et al. 2006; Cueni, Canepari et al. 2008; Lin, Lujan et al. 2008). Despite the recent progress on SK channel physiology, the precise spatial organization of SK …
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Intracellular sphingosine kinase activity as a regulator of endothelial cell inflammatory and angiogenic potential.
… levels and activity of Sphingosine Kinase (SK) regulate the inflammatory potential of the endothelium and are also an important determinant of the ability of the endothelium to undergo angiogenesis. Moderate (three to fivefold) elevations in SK activity in human umbilical vein endothelial …
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Human Neuroblastoma, Strain Sk-N-Sh, as a Model System of Nerve Cell Differentiation: Neuronal Development, Plasminogen Activator Release, and Unscheduled Deoxyribonucleic Acid Synthesis
… of the cultured human neuroblastoma, strain SK-N-SH, maintained in vitro. In complete growth medium supplemented with 15% fetal bovine serum, SK-N-SH cells exhibited a large nucleus, with several distinct nucleoli, and neurite- and dendrite-like processes with branched end terminals. Within a …
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Dreidimensionale Rekonstruktion einer exzitatorischen zentralen Synapse : die Held`sche Calyx - Prinzipalneuron Synapse im medialen Nucleus des Trapezkörpers
… (MS) identifiziert: die synaptischen Kontakte (SK), die aus den aktiven Zonen (AZ) und den dazugehörigen postsynaptischen Dichten (PSD) bestanden, und die puncta adhaerentia (PA). Ungefähr 35% der MS konnten als SK (n = 554), die verbleibenden 65% als PA (n = 1010) klassifiziert werden. Die SK …
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Land use and its impact on the Succulent Karoo
The Succulent Karoo biome (SK biome) is one of the 25 internationally recognized biodiversity hotspots in South Africa with approximately 1940 endemic species. The SK biome is, however, poorly conserved with less than 5% of the area under formal protection. It is also highly threatened by a range …
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Adoption of Aspiration Feature in Sino-Korean Phonology
… irregularly into Sino-Korean, and Sino-Korean (SK) readings with aspiration discrepancy are part of this broader phenomenon of irregular SK readings. It is generally assumed that both the Chinese and Korean languages had voiceless aspirated stops and voiceless unaspirated stops at the time …
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Protein-Protein-Interaktionen in den 'Gating'-Domänen von Kaliumkanälen
… bzw. Deaktivierung von Ca2+-gesteuerten SK-Kanälen sowie die Inaktivierung von spannungsgesteuerten Kv-Kanälen. Die einzelnen Projekte wurden in interdisziplinärer Zusammenarbeit mit Wissenschaftlern aus derselben und anderen Arbeitsgruppen durchgeführt. <br>Der Schwerpunkt lag auf der …
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Ecological Sustainability of Winter Harvesting in the Duck Mountain Provincial Park, SK: The Effects of Skidder Traffic, Slash Loading, and Cumulative Effects on Soils and Aspen Regeneration
… practice for successful aspen regeneration. Skidder traffic intensity, slash coverage, and vegetation indices were calculated for six harvested blocks using Global Positioning Systems (GPS), Unoccupied Aerial Vehicles (UAVs) and Geographic Information Systems (GIS). Based on this information, …
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Signaling between Two Sensor Kinases Controls Biofilms and Host Colonization in a Bacterial Symbiont
… of an environmental sensor (the sensor kinase, SK) and a cognate, intracellular effector (the response regulator, RR). The marine bacterium Vibrio fischeri uses an elaborate TCS phosphorelay containing a hybrid SK, RscS, and two RRs, SypE and SypG, to colonize its natural squid host, Euprymna …
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Engineered quantum dots for infrared photodetectors
… fabrication technology. However, due to Stranski-Krastanov (SK) growth mode and the subsequent capping growth, the conventional SK QDs are pancake shaped' with small height to base ratio due to interface diffusion. Thus they cannot fully exploit the 3D 'artificial atom' properties. This …
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Culture of dimethylhydrazine induced murine angiosarcoma and an evaluation of anti-angiogenic therapy of primary tumor and of tumor metastasisLa mise en culture d'angiosarcomes murins induits par le diméthylhydrazine et l'évaluation du traitement anti-angiogénique de tumeurs primaires et métastasiques
… du sarcome de Kaposi associé au SIDA (SK SIDA) a peu évolué jusqu'à maintenant à cause de l'absence d'un modèle animal satisfaisant. La tumeur humaine ne prolifère pas lorsque transplantée chez la souris nue et des tumeurs spontanées semblables au SK SIDA n'ont pas encore été …
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