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Showing 1 to 2 of 2 for “"SIR-2.1"”.

  1. C.ELEGANS HOST CELL FACTOR (CeHCF) ASSOCIATES WITH SIR-2.1 TO MEDIATE TARGET SPECIFICITY OF DAF-16 AND LIFESPAN

    Yao, Yao

    clemson Repository record

  2. Identification of new genes and pathways that act to delay C. elegans aging

    Berdichevsky, AlinaMassachusetts Institute of Technology2008

    … have investigated the mechanism of action of the sir-2.1 gene, which extends C. elegans lifespan when overexpressed. We discovered that sir-2.1 acts to promote longevity in parallel to low insulin signaling, in a stress-dependent pathway that converges with the insulin-like pathway on a forkhead …

    mit Repository record