Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"SIM1"”.
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The bHLH/PAS Transcription Factor SIM1 Is a Novel Obesity Gene
… disrupts a transcription factor gene, SIM1, on chromosome 6q16.2. I also present data that Sim1 haploinsufficiency causes obesity in mice. Animals heterozygous for a Sim1 null allele fed a standard chow diet (4% fat) developed obesity around the time of sexual maturity, were 33-45% …
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Investigating mechanisms and biological functions of the bHLH/PAS transcription factors SIM1 and ARNT2
… partner protein of ARNT2 to be Single-Minded 1 (SIM1), a bHLH/PAS factor predominately expressed in the paraventricular nucleus (PVN) and supraoptic nucleus (SON) of the hypothalamus. SIM1 has been established to be essential in the developing hypothalamus and has a physiological role in appetite …
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A Study on Quenching and Galaxy Growth in z~1 Clusters using HST WFC3 Grism Observations
… and G141 grism data on 10 galaxy clusters at $z\sim1$ to study how the quenching of star formation in galaxies and galaxy size growth operates in different environments at this redshift. The unique capabilities of space-based slitless spectroscopy with the G141 grism allows for the construction …
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Power-law liquid in high-temperature superconductors
… The scaling exponent decreases from $\alpha\sim1$ in the overdoped Fermi-liquid state to $\alpha\lesssim\frac{1}{2}$ in the optimal and underdoped regime. We find that broad scale invariance of a power-law liquid leads to the cuprates' superconducting dome, vanishing Fermi velocity, and …
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Insights into the nature of dust attenuation in relation to galaxy evolution from local to cosmic noon galaxies
… with observations of galaxies at cosmic noon ($z\sim1-3$) from the Keck telescope and the Very Large Telescope, finding that there is no significant evolution in the relationship between the dust attenuation and the stellar mass. This indicates that the dust production mechanism connected to the …