Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"SIGLEC-G"”.
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Investigating the antibody-independent functions of B lymphocytes
… attract inflammatory monocytes. The absence of Siglec-G, an inhibitory receptor expressed in innate B1a cells, exacerbates AKI in murine models. Conversely, concomitant administration of a Siglec-G agonist, sialic acid (Neu5AC), ameliorated AKI and reduced renal neutrophil infiltration. These …
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Investigating the phenotype and function of tissue-resident B cells in mouse and human non-lymphoid organs
… modified mice with higher (PI3Kδ E1020K-B, Siglec-G-/-) or lower (μMT-) numbers of tissue-resident B cells in NLOs, we tested the function of these cells in the context of urinary tract infection. The number of tissue-resident B cells inversely correlated with bacterial clearance suggesting …