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Showing 1 to 1 of 1 for “"SHC1"”.

  1. The Role of p66Shc in Stem Cells: Signalling, Identity and Apoptosis

    Adaptor proteins of the Shc family link receptor tyrosine kinases (RTKs) to downstream signalling, thereby shaping cell fate decisions. While the canonical isoforms p52Shc and p46Shc act as Ras–MAPK transducers, the longer p66Shc isoform harbours an additional CH2 domain that confers distinct …

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