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Showing 1 to 20 of 22 for “"SHBG"”.

  1. Computational ligand discovery for the human and zebrafish sex hormone binding globulin

    Thorsteinson, NelsUniversity of British Columbia2008

    … and zebrafish sex hormone binding globulin (SHBG). The ‘benchmark set of steroids’ is a set of steroids with known affinities for human SHBG that has been widely used for validation in the development of different virtual screening methods. We have updated this data set by including …

    ubc Repository record

  2. The Association Between Sex Hormone Binding Globulin And C-Reactive Protein Levels in Premenopausal Women

    Al-Lami, Rasha Azeez HammoodThe University of Texas Medical Branch at Galveston2020

    … process. Sex Hormone Binding Globulin (SHBG) modulates the relative effects of estrogen and testosterone, specifically promoting estrogen effects systemically. Furthermore, estrogen enhances the synthesis of SHBG and was reported to have a role in immune modulation. Thus, it is believed …

    utmb Repository record

  3. Imaging Prostate Cancer: Design, Synthesis, and in Vivo Testing of Steroidal and Non-Steroidal Androgen Selective PET Radiopharmaceuticals

    Parent, Ephraim EdwardUniversity of Illinois at Urbana-Champaign2015

    … mechanism. Sex hormone binding globulin (SHBG) binds testosterone, the principal circulating androgen, in high affinity and is believed to be directly involved in delivery of the hormone to cytoplasmic AR. Other high-affinity AR compounds, such as nor-testosterone, do not bind SHBG and …

    uiuc Repository record

  4. Regional Fat Distribution, Physical Activity and Hormonal Factors in Adults With Type 2 Diabetes

    Pascale, AngeloUniversity of Illinois at Urbana-Champaign2015

    … radioimmunoassay. Sex-hormone binding globulin (SHBG), and androgeneicity index (AI) were calculated from testosterone and FT. Leisure, occupational, household, non-leisure and total physical activity (TPA) at time1 (15--22 years of age), time2 (23--34 years), time3 (35--50 years), and time4 …

    uiuc Repository record

  5. Androgen Levels in Men with Acute and Chronic Coronary Syndrome // Андрогенни нива при мъже с остър и хроничен коронарен синдром

    Шишков, Сави, Shishkov, SaviMedical University of Varna2023

    … с някои липидни показатели. По-ниските нива на SHBG се свързват с по-лош метаболитен профил в групата ХКС, докато в ОКС по-високите нива на SHBG са параметър отразяващ и допълващ рисковата характеристика. Основни детерминанти на DHEA-S са възрастта и гломерулната филтрация в групите ОКС и АКБ, …

    varna Repository record

  6. Nanoparticelle di biossido di titanio: tossicità e possibile ruolo come interferenti endocrini

    SCALISI, ELENA MARIAUniversità degli studi di Catania2022

    … e i biomarker Sex hormone-binding globulin (SHBG), Prothymosin-α (PTMA) che suggeriscono l’azione delle TiO2-NPs come interferenti endocrini. Per tutto il periodo dell’esposizione sono stati valutati i tassi di uova coagulate e schiuse, e cambiamenti nel fenotipo delle larve come la lunghezza …

    catania Repository record

  7. The relationship between reproductive hormones and asthma-related outcomes in boys residing in the rural Western Cape

    Phuti, MandyDepartment of Public Health and Family Medicine2023

    … oestradiol and serum hormone-binding globulin (SHBG), were assessed using electrochemiluminescence immunoassays. A total of 314 (66.8%) boys had valid asthma outcome information and hormone level measurements that were analysed further. Multivariate logistic regression models were used to assess …

    cape-town Repository record

  8. Naturstoff-basierte Cytostatika mit verbesserter Tumorselektivität und Potential zur Überwindung von Wirkstoffresistenzen

    Biersack, BernhardUniversität Bayreuth

    … dieser Arbeit ihre Bindung an das Serumprotein SHBG optimiert, welches Estrogene und Androgene im Blut transportiert und im Zielgewebe akkumuliert. Eine erste Serie von Steroid-Konjugaten mit Pt(II)-Komplexen wies deutliche Struktur-Aktivitäts-Beziehungen hinsichtlich der Affinität zu SHBG auf. …

    bayreuth Repository record

  9. Επίπεδα ανδρογόνων σε έφηβες: συσχέτιση με τα στάδια σεξουαλικής ανάπτυξης κατά Tanner

    Καραγκούνη Μαρία, Karagkouni Maria2026

    … συσχέτιση των επιπέδων ανδρογόνων (τεστοστερόνη, SHBG, DHEA-S, DHEA, Δ4-ανδροστενδιόνη, 17-OH προγεστερόνη) με τα στάδια Tanner (μαστού, εφηβαίου και μασχάλης) σε έφηβα κορίτσια και (2) να εξεταστεί κατά πόσο οι αυξημένες τιμές ανδρογόνων σχετίζονται με την παρουσία κλινικών εκδηλώσεων …

    athens Repository record

  10. I. Synthesis of Myocardial Imaging Agents for Diagnosis of MCAD Deficiency. II. Synthesis of [fluorine-18] Fluoroaryl Estrogens as Receptor Based Tumor Imaging Agents for Breast Cancer

    Hostetler, Eric DaleUniversity of Illinois at Urbana-Champaign2015

    … it must be administered to animals possessing SHBG.

    uiuc Repository record

  11. The relationship between gonadal hormones and neurocognitive functioning in healthy men and women and patients with schizophrenia

    Halari, R.City University London2003

    … hormones; FSH) and sex hormone binding globulin; SHBG to these cognitive tasks. Study 2 investigated the role of gonadal hormones and the stress hormone cortisol to neurocognitive functioning (comprising domains of attention, verbal abilities, language, memory, executive functioning, motor and …

    city-london Repository record

  12. Effekt von Amiodaron auf periphere Parameter der Schilddrüsenhormonaktivität bei kardiologischen Patienten mit AICD

    Wünsche, Christoph2012

    … bAP, Osteokalzin, PIIINP, für Leber und Lipide: SHBG, GGT, Ferritin, Albumin, Cholesterin und für Muskel bzw. Herz: CK, CK-MB. Im Ergebnis erbrachte der Knochenaufbauparameter CICP als einziger Antwortparameter einen signifikanten, für die hypothyreote Stoffwechsellage typischen Unterschied zur …

    goettingen Repository record

  13. Adiponectin and Some Other Metabolic Risk Markers and Their Relation to Abdominal Obesity in Preschool Children // Адипонектин и някои други маркери на метаболитен риск и тяхната връзка с абдоминалното затлъстяване при деца в предучилищна възраст

    Латева, Мина, Lateva, MinaMedical University of Varna2019

    … дават стабилни данни за използването на SHBG като метаболитен рисков маркер, свързан със затлъстяването. С подобно значение е и CRP. Утвърдените при възрастни и юноши адипокини като маркери за метаболитен риск, според данните от настоящото изследване са приложими и в тази възрастова …

    varna Repository record

  14. TOTAL AND ABDOMINAL OBESITY - PRENATAL AND POSTNATAL INFUENCES. SIGNIFICANCE FOR THE IMPAIRED RISK PROFILE FROM CHILDHOOD // ОБЩО И АБДОМИНАЛНО ЗАТЛЪСТЯВАНЕ - ПРЕНАТАЛНИ И ПОСТНАТАЛНИ ВЛИЯНИЯ. ЗНАЧЕНИЕ ЗА ПОВИШЕНИЯ РИСКОВ ПРОФИЛ ОТ ДЕТСКА ВЪЗРАСТ

    Йотова, Виолета, Iotova, VioletaMedical University of Varna2019

    … както и редица метаболитни маркери (адипонектин, SHBG, инсулинова резистентност - HOMA-IR, TNF-alfa, IL-6, полови стероиди и DHEA-S). Всички те са значимо влошени при иначе здрави МГВ деца, като най-лоши са показателите на тези, които са натрупали най-много мазнини Извършено е сравнение данни от …

    varna Repository record

  15. Η επίδραση της κετοκοναζόλης στην ιδιοπαθή ορμονοεξαρτώμενη τριχοφυΐα

    Δοξανίδης, ΕμμανουήλAristotle University Of Thessaloniki (AUTH)1990

    … included measurements of Testosterone, DHEA-S, SHBG and A4-Androstenedione. The above profile showed a considerable variation within the population. Nonetheless certain patterns of hormonal changes were noticed between the patients. [...]

    greece Repository record

  16. Longitudinal study to assess the prevalence of hypogonadism in HIV-infected South African men and its association with bone density, body composition, metabolic abnormalities (dysglycaemia, dyslipidaemia) and quality of life.

    van Der Merwe, Le RouxDivision of Endocrinology and Diabetology2021

    … Here we report on total testosterone, LH, FSH, SHBG and free testosterone measured on blood samples taken at 08h00 prior to initiating ART (baseline) and then again at 12 months on ART. Results: There were 44 patients at baseline and 30 patients at the 12-month visit. There were no participants …

    cape-town Repository record

  17. Anthropometric measurements, sexual development and serum reproductive hormonal levels among boys in the rural Western Cape

    Mao, JunInstitute of Infectious Disease and Molecular Medicine2016

    … testosterone, sex hormone binding globulin (SHBG) and estradiol (E2); a physical examination of height, weight and BMI measurements; sexual matura tional assessment and a questionnaire (demographics and general medical history). Median of anthropometric variables and hormone levels by …

    cape-town Repository record

  18. Evaluation of the Pharmacokinetic-Pharmacodynamic relationship, Metabolism and Plasma Protein Binding of the novel antitumor agent, 2-Methoxyestradiol (2ME2), following oral administration in patients with solid tumors.

    Lakhani, Nehal Jagdish2014

    … (AAG) and sex-hormone binding globulin (SHBG).

    vcu Repository record

  19. The Impact of Acute and Chronic Weight Restriction and Weight Regulation practices on Physiological, Osteogenic, Metabolic and Cognitive Function in Elite Jockeys

    Dolan, EimearDublin City University2010

    … resorption increased in a jockey group. Elevated SHBG and reduced IGF-1 levels in comparison to an age, gender and BMI matched control group appeared to have a role to play in this finding. No aspect of body composition, bone mass or turnover was affected by the vibration therapy protocol used …

    dcu Repository record

  20. Epidemiological investigations of liver cancer: biomarkers, reproductive factors and modifiable risk factors:

    Tran, Kim TuQueen's University Belfast2020

    … men who had higher levels of testosterone and SHBG had higher risk of liver cancer, specifically of HCC, but this association was not found in women. <br/><br/>In summary, the current thesis has contributed to the literature by identifying new risk factors for liver cancer and clarifying …

    qu-belfast Repository record

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